PANTHER Gene Information   
Gene Symbol(s): Dio3
Organism: Mus musculus
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Gene Name: Thyroxine 5-deiodinase
Gene ID: MGI:1306782
Protein ID: Q91ZI8
Persistent Id: PTN000207382
Alternate Ids:
ENSMUSP00000133920(Ensembl_PRO) 107585(GeneID)
Dio3(Symbol) DIOIII(Synonym)
AL591207(EMBL) ENSMUST00000173014(Ensembl_TRS)
ENSMUSG00000075707(Ensembl) AAL23960(EMBL-CDS)
1.21.99.3(EC) 76827837(GI)
G3UY28(AltAccession) NP_742117(refSeq)
MGI:1306782(MGI) IOD3_MOUSE(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: IODOTHYRONINE DEIODINASE (PTHR11781)
PANTHER Subfamily: THYROXINE 5-DEIODINASE (PTHR11781:SF4)  
PANTHER GO-slim Molecular Function: oxidoreductase activity
PANTHER GO-slim Biological Process: organic cyclic compound metabolic process
cellular modified amino acid metabolic process
hormone metabolic process
cellular aromatic compound metabolic process
organic hydroxy compound metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class: metabolite interconversion enzyme
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: thyroxine 5'-deiodinase activity, thyroxine 5-deiodinase activity
GO BP Complete: thyroid hormone catabolic process, retinal cone cell apoptotic process, response to hypoxia, brown fat cell proliferation, apoptotic process, retinal cone cell development, positive regulation of multicellular organism growth, hormone biosynthetic process, thyroid hormone metabolic process
GO CC Complete: intracellular membrane-bounded organelle, endosome membrane, plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Regulation of thyroid hormone activity, Thyroxine biosynthesis, Metabolism, Metabolism of amine-derived hormones, Metabolism of amino acids and derivatives

Orthologs