PANTHER Gene Information

Gene Symbol(s):

Il12rb2

Organism:

Mus musculus

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Gene Name:

Interleukin-12 receptor subunit beta-2

Gene ID:

MGI:1270861

Protein ID:

P97378

Persistent Id:

PTN000547554

Alternate Ids:

ENSMUSG00000018341(Ensembl)	IL-12R-beta-2(Synonym)
XM_006505617(refSeq)	902763375(GI)
B9EHD9(AltAccession)	MGI:1270861(MGI)
16162(GeneID)	ENSMUST00000018485(Ensembl_TRS)
Il12rb2(Symbol)	ENSMUSP00000010605(Ensembl_PRO)
BC137745(EMBL)	I12R2_MOUSE(UniProtKB-ID)
AAI37746(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	CYTOKINE RECEPTOR (PTHR23036)
PANTHER Subfamily:	INTERLEUKIN-12 RECEPTOR SUBUNIT BETA-2 (PTHR23036:SF79)
PANTHER GO-slim Molecular Function:	cytokine binding cytokine receptor activity
PANTHER GO-slim Biological Process:	cytokine-mediated signaling pathway
PANTHER GO-slim Cellular Component:	receptor complex external side of plasma membrane
PANTHER protein class:	transmembrane signal receptor

Pathway Categories:

Interleukin signaling pathway

Interleukin receptor beta subunit

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	coreceptor activity, protein kinase binding, protein binding, cytokine receptor activity, cytokine binding
GO BP Complete:	response to cytokine, peptidyl-tyrosine phosphorylation, type II interferon production, cytokine-mediated signaling pathway, positive regulation of cell population proliferation, positive regulation of type II interferon production, response to lipopolysaccharide, interleukin-12-mediated signaling pathway
GO CC Complete:	external side of plasma membrane, receptor complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Immune System, Interleukin-12 family signaling, Interleukin-12 signaling, Signaling by Interleukins, Interleukin-35 Signalling, Cytokine Signaling in Immune system

Orthologs

ID	Organism	Type
HUMAN\|HGNC=5972\|UniProtKB=Q99665	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000840.6\|UniProtKB=H2PZ74	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006395.3\|UniProtKB=G3QU59	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000651.4\|UniProtKB=F6X0C8	Macaca mulatta	LDO
RAT\|RGD=620026\|UniProtKB=F1LRH7	Rattus norvegicus	LDO
BOVIN\|Gene=IL12RB2\|UniProtKB=Q9BEG2	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000009455.6\|UniProtKB=F1MEB5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000003799.6\|UniProtKB=F1S826	Sus scrofa	O
PIG\|Gene=IL12RB2\|UniProtKB=Q8MJS1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016537.4\|UniProtKB=F6YRY6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001940.6\|UniProtKB=M3VXK8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845026911.1\|UniProtKB=A0A8I3PVV0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000000859.4\|UniProtKB=F7BHT6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007768.3\|UniProtKB=A0A6I8MXA7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023249.1\|UniProtKB=A0A8V0ZVG0	Gallus gallus	LDO
XENLA\|Gene=LOC108715519\|UniProtKB=A0A8J1KIY0	Xenopus laevis	O
XENLA\|Gene=LOC108714211\|UniProtKB=A0A8J0V5X5	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000043084\|UniProtKB=A0A803K8B3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000015026.2\|UniProtKB=H2MJI4	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000007083.1\|UniProtKB=W5MJL6	lepisosteus oculatus	O
BRAFL\|Gene=LOC118419505\|UniProtKB=A0A9J7LG31	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429283\|UniProtKB=A0A9J7NAS6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429282\|UniProtKB=A0A9J7M7H3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420158\|UniProtKB=A0A9J7MWN7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431483\|UniProtKB=A0A9J7MCB2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432370\|UniProtKB=A0A9J7MFK4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411648\|UniProtKB=A0A9J7KUW9	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100891084\|UniProtKB=A0A7M7HL64	Strongylocentrotus purpuratus	O
CAEBR\|Gene_ORFName=CBG05054\|UniProtKB=A8WZ26	Caenorhabditis briggsae	O
TRICA\|EnsemblGenome=TC001874\|UniProtKB=D7EJN5	Tribolium castaneum	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g203857\|UniProtKB=A7RY42	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g242037\|UniProtKB=A7S0R0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g207296\|UniProtKB=A7S5X5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g248399\|UniProtKB=A7T0T0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g206807\|UniProtKB=A7S4S8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g59990\|UniProtKB=A7RNY4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g96874\|UniProtKB=A7RXR5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g204357\|UniProtKB=A7RZ85	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g2043\|UniProtKB=A7SZ31	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG53774\|UniProtKB=B3RQ47	Trichoplax adhaerens	O