PANTHER Gene Information   
Gene Symbol(s): Pde1a
Organism: Mus musculus
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Gene Name: Dual specificity calcium_calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Gene ID: MGI:1201792
Protein ID: Q61481
Persistent Id: PTN000142365
Alternate Ids:
U56649(EMBL) EDL27256(EMBL-CDS)
Cam-PDE 1A(Synonym) Pde1a{ECO:0000312|MGI:MGI:1201792}(Symbol)
XP_006498984(refSeq) 18573(GeneID)
PDE1A_MOUSE(UniProtKB-ID) O35388(AltAccession)
3.1.4.17 {ECO:0000269|PubMed:15901640}(EC) MGI:1201792(MGI)
ENSMUSG00000059173(Ensembl) 148695309(GI)
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PANTHER Classification
PANTHER Family: CYCLIC NUCLEOTIDE PHOSPHODIESTERASE (PTHR11347)
PANTHER Subfamily: DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1A (PTHR11347:SF34)  
PANTHER GO-slim Molecular Function: cyclic-nucleotide phosphodiesterase activity
PANTHER GO-slim Biological Process: cAMP-mediated signaling
PANTHER GO-slim Cellular Component: neuronal cell body
PANTHER protein class: phosphodiesterase
Pathway Categories: CCKR signaling map
   PDE
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity, calmodulin binding, 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity, metal ion binding, calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity, 3',5'-cyclic-GMP phosphodiesterase activity, 3',5'-cyclic-AMP phosphodiesterase activity
GO BP Complete: regulation of smooth muscle cell proliferation, regulation of smooth muscle cell apoptotic process, signal transduction, cGMP catabolic process, cAMP-mediated signaling
GO CC Complete: motile cilium, neuronal cell body, sperm flagellum
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: G alpha (i) signalling events, Signal Transduction, cGMP effects, Platelet homeostasis, G alpha (s) signalling events, Intracellular signaling by second messengers, G-protein mediated events, GPCR downstream signalling, Calmodulin induced events, Ca-dependent events, CaM pathway, Nitric oxide stimulates guanylate cyclase, Hemostasis, Cam-PDE 1 activation, PLC beta mediated events, DAG and IP3 signaling, Signaling by GPCR, Opioid Signalling

Orthologs