PANTHER Gene Information   
Gene Symbol(s): Rnf2
Organism: Mus musculus
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Gene Name: E3 ubiquitin-protein ligase RING2
Gene ID: MGI:1101759
Protein ID: Q9CQJ4
Persistent Id: PTN000088749
Alternate Ids:
BAB28663(EMBL-CDS) Y12783(EMBL)
26354897(GI) ENSMUSG00000026484(Ensembl)
2.3.2.27 {ECO:0000269|PubMed:15525528, ECO:0000269|PubMed:22325148, ECO:0000269|PubMed:24980959}(EC) RING finger protein 2(Synonym)
O35729(AltAccession) NM_011277(refSeq)
MGI:1101759(MGI) RING2_MOUSE(UniProtKB-ID)
19821(GeneID) ENSMUSP00000140896(Ensembl_PRO)
ENSMUST00000076110(Ensembl_TRS) Rnf2(Symbol)
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PANTHER Classification
PANTHER Family: E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER (PTHR46076)
PANTHER Subfamily: E3 UBIQUITIN-PROTEIN LIGASE RING2 (PTHR46076:SF4)  
PANTHER GO-slim Molecular Function: chromatin binding
ubiquitin protein ligase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component: ubiquitin ligase complex
PcG protein complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ubiquitin-protein transferase activity, zinc ion binding, ubiquitin protein ligase activity, protein binding, RING-like zinc finger domain binding, histone H2AK119 ubiquitin ligase activity, chromatin binding
GO BP Complete: negative regulation of transcription by RNA polymerase II, germ cell development, anterior/posterior axis specification, chromatin remodeling, gastrulation with mouth forming second, gene expression, negative regulation of DNA-binding transcription factor activity, chromatin organization, mitotic cell cycle, epigenetic regulation of gene expression, protein ubiquitination
GO CC Complete: heterochromatin, nucleus, euchromatin, nuclear body, PRC1 complex, ubiquitin ligase complex, cytoplasm, PcG protein complex, sex chromatin, nucleoplasm, MLL1 complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: SUMO E3 ligases SUMOylate target proteins, Transcriptional Regulation by E2F6, SUMOylation of DNA damage response and repair proteins, Generic Transcription Pathway, Gene expression (Transcription), SUMOylation of transcription cofactors, SUMOylation of RNA binding proteins, Transcriptional regulation by RUNX1, SUMOylation of chromatin organization proteins, RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known, Metabolism of proteins, Post-translational protein modification, SUMOylation, RNA Polymerase II Transcription

Orthologs