PANTHER Gene Information

Gene Symbol(s):

Mid1

Organism:

Mus musculus

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Gene Name:

E3 ubiquitin-protein ligase Midline-1

Gene ID:

MGI:1100537

Protein ID:

O70583

Persistent Id:

PTN000647422

Alternate Ids:

17318(GeneID)	TRI18(Synonym)
TRI18_MOUSE(UniProtKB-ID)	MGI:1100537(MGI)
2.3.2.27(EC)	Q7TPT6(AltAccession)
ENSMUSG00000035299(Ensembl)	594190974(GI)
AAB83986(EMBL-CDS)	Y14848(EMBL)
Mid1(Symbol)
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PANTHER Classification

PANTHER Family:	E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED (PTHR24099)
PANTHER Subfamily:	E3 UBIQUITIN-PROTEIN LIGASE MIDLINE-1 (PTHR24099:SF23)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	regulation of microtubule cytoskeleton organization
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	zinc ion binding, identical protein binding, protein binding, ubiquitin protein ligase binding, protein homodimerization activity, phosphoprotein binding, transferase activity, microtubule binding, enzyme binding
GO BP Complete:	regulation of microtubule cytoskeleton organization, protein localization to microtubule, negative regulation of microtubule depolymerization, positive regulation of stress-activated MAPK cascade
GO CC Complete:	microtubule cytoskeleton, cytoplasm, centriolar satellite, cytosol, Golgi apparatus, cytoplasmic microtubule, microtubule

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7095\|UniProtKB=O15344	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000021656.6\|UniProtKB=A0A2I3SM24	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003756.3\|UniProtKB=G3QMF3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000020179.4\|UniProtKB=F6WCI4	Macaca mulatta	LDO
RAT\|RGD=2640\|UniProtKB=P82458	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000010152.6\|UniProtKB=E1BAD8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005005585.1\|UniProtKB=A0A5G2R4L4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019648.4\|UniProtKB=F7CLC3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002582.6\|UniProtKB=M3VYS6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845026369.1\|UniProtKB=A0A8I3PU57	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017399.4\|UniProtKB=F6SKS1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002628.4\|UniProtKB=F6SKR8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010002012.1\|UniProtKB=A0A8V0X812	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001219.4\|UniProtKB=G1K9B6	Anolis carolinensis	LDO
XENLA\|Gene=mid1.L\|UniProtKB=D8WX02	Xenopus laevis	O
XENLA\|Gene=mid1.S\|UniProtKB=A0A1L8H6I9	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-494584\|UniProtKB=Q6DEU6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000017792.2\|UniProtKB=H2MU11	Oryzias latipes	LDO
ORYLA\|Ensembl=ENSORLG00000004661.2\|UniProtKB=H2LIN6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-110411-205\|UniProtKB=A0A8M3AWB4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007293.1\|UniProtKB=W5MKC6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008591.3\|UniProtKB=F6UD02	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118406094\|UniProtKB=A0A9J7HLU9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118425437\|UniProtKB=A0A9J7LXG6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118416176\|UniProtKB=A0A9J7MSF2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423086\|UniProtKB=A0A9J7N1L2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118404977\|UniProtKB=A0A9J7KI94	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422179\|UniProtKB=A0A9J7LPJ1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118416248\|UniProtKB=A0A9J7L6V2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418462\|UniProtKB=A0A9J7LCB5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429705\|UniProtKB=A0A9J7M7T3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406249\|UniProtKB=A0A9J7HPK9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421686\|UniProtKB=A0A9J7LLZ6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118424720\|UniProtKB=A0A9J7N4L4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100890735\|UniProtKB=A0A7M7PS89	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00016539\|UniProtKB=Q9UAQ3	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024366\|UniProtKB=A8WPI5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00116453\|UniProtKB=A0A8R1UG85	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0051721\|UniProtKB=M9MRI4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029914\|UniProtKB=A0A903XX56	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC007563\|UniProtKB=D2A382	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_225606\|UniProtKB=E9GS33	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG117052\|UniProtKB=T1EGJ7	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g107944\|UniProtKB=A7S7Q5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g104795\|UniProtKB=A7S501	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG61254\|UniProtKB=B3SAG8	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_6293\|UniProtKB=A9UTE6	Monosiga brevicollis	O
CHLRE\|EnsemblGenome=CHLRE_07g338300v5\|UniProtKB=A0A2K3DKB5	Chlamydomonas reinhardtii	O
SELML\|EnsemblGenome=SELMODRAFT_446250\|UniProtKB=D8SPU9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_444263\|UniProtKB=D8S8I1	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c22_1540\|UniProtKB=A9T487	Physcomitrella patens	O
KLENI\|Gene_ORFName=KFL_007150060\|UniProtKB=A0A1Y1IS88	Klebsormidium nitens	O