PANTHER Gene Information   
Gene Symbol(s): Vps4b
Organism: Mus musculus
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Gene Name: Vacuolar protein sorting-associated protein 4B
Gene ID: MGI:1100499
Protein ID: P46467
Persistent Id: PTN000553932
Alternate Ids:
3.6.4.6(EC) NM_009190(refSeq)
ENSMUSG00000009907(Ensembl) 557876(GI)
U10119(EMBL) AAH03799(EMBL-CDS)
Vps4b{ECO:0000312|MGI:MGI:1100499}(Symbol) ENSMUST00000112736(Ensembl_TRS)
ENSMUSP00000108356(Ensembl_PRO) VPS4B(Synonym)
MGI:1100499(MGI) 20479(GeneID)
Q9R1C9(AltAccession) VPS4B_MOUSE(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: AAA DOMAIN-CONTAINING (PTHR23074)
PANTHER Subfamily: VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4B (PTHR23074:SF72)  
PANTHER GO-slim Molecular Function: ATP hydrolysis activity
PANTHER GO-slim Biological Process: vacuole organization
endosomal transport
PANTHER GO-slim Cellular Component:
PANTHER protein class: non-motor microtubule binding protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP hydrolysis activity, ATP binding, identical protein binding, protein binding, protein homodimerization activity, protein-containing complex binding
GO BP Complete: ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway, endosome organization, negative regulation of exosomal secretion, vacuole organization, positive regulation of exosomal secretion, protein transport, vacuolar transport, late endosomal microautophagy, midbody abscission, positive regulation of centriole elongation, potassium ion transport, viral budding from plasma membrane, angiogenesis, autophagy, endosomal transport, canonical Wnt signaling pathway, response to lipid, cholesterol transport, positive regulation of G2/M transition of mitotic cell cycle, membrane fission, regulation of mitotic spindle assembly, protein depolymerization, establishment of blood-brain barrier, late endosome to lysosome transport via multivesicular body sorting pathway, nucleus organization, ESCRT III complex disassembly, autophagosome maturation, central nervous system development, regulation of centrosome duplication, plasma membrane repair, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, multivesicular body sorting pathway, endosome to lysosome transport via multivesicular body sorting pathway, nuclear membrane reassembly, multivesicular body assembly, viral budding via host ESCRT complex, mitotic metaphase chromosome alignment
GO CC Complete: Flemming body, spindle pole, plasma membrane, nuclear pore, nucleus, late endosome membrane, centrosome, endosome, ATPase complex, cytoplasm, cytosol, endosome membrane, midbody
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Endosomal Sorting Complex Required For Transport (ESCRT), Vesicle-mediated transport, Membrane Trafficking

Orthologs