PANTHER Gene Information   
Gene Symbol(s): Ercc6
Organism: Mus musculus
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Gene Name: DNA excision repair protein ERCC-6
Gene ID: MGI:1100494
Protein ID: F8VPZ5
Persistent Id: PTN002246111
Alternate Ids:
MGI:1100494(MGI) Csb(Synonym)
A3KMN2(AltAccession) ERCC6_MOUSE(UniProtKB-ID)
3.6.4.- {ECO:0000250|UniProtKB:Q03468}(EC) XM_006519120(refSeq)
ENSMUSG00000054051(Ensembl) 568987900(GI)
AC154412(EMBL) AAI32448(EMBL-CDS)
Ercc6(Symbol) ENSMUST00000066807(Ensembl_TRS)
319955(GeneID) ENSMUSP00000066256(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: SNF2/RAD54 FAMILY MEMBER (PTHR45629)
PANTHER Subfamily: DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED (PTHR45629:SF7)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class: damaged DNA-binding protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP hydrolysis activity, RNA polymerase binding, DNA binding, ATP binding, ATP-dependent activity, acting on DNA, ATP-dependent chromatin remodeler activity, protein tyrosine kinase activator activity, helicase activity, sequence-specific DNA binding, chromatin binding
GO BP Complete: multicellular organism growth, DNA repair, response to X-ray, negative regulation of double-strand break repair via nonhomologous end joining, base-excision repair, transcription elongation by RNA polymerase I, positive regulation of transcription initiation by RNA polymerase II, transcription-coupled nucleotide-excision repair, positive regulation of peptidyl-serine phosphorylation of STAT protein, positive regulation of double-strand break repair via homologous recombination, JNK cascade, response to UV, neurogenesis, positive regulation of transcription by RNA polymerase II, response to toxic substance, positive regulation of transcription by RNA polymerase III, positive regulation of transcription by RNA polymerase I, response to oxidative stress, chromatin remodeling, DNA protection, photoreceptor cell maintenance, regulation of DNA-templated transcription elongation, response to gamma radiation, positive regulation of DNA-templated transcription, elongation, positive regulation of DNA repair, pyrimidine dimer repair, neuron differentiation, neuron projection development, regulation of transcription elongation by RNA polymerase II, intrinsic apoptotic signaling pathway in response to DNA damage, response to superoxide, positive regulation of defense response to virus by host, DNA damage response, double-strand break repair via classical nonhomologous end joining, single strand break repair, DNA damage checkpoint signaling, positive regulation of gene expression, response to UV-B
GO CC Complete: nucleus, site of DNA damage, B-WICH complex, nuclear body, transcription elongation factor complex, nucleolus, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Transcription-Coupled Nucleotide Excision Repair (TC-NER), Nucleotide Excision Repair, B-WICH complex positively regulates rRNA expression, Positive epigenetic regulation of rRNA expression, Gene expression (Transcription), Epigenetic regulation of gene expression, RNA Polymerase I Transcription Initiation, DNA Repair, RNA Polymerase I Transcription, Gap-filling DNA repair synthesis and ligation in TC-NER, Formation of TC-NER Pre-Incision Complex, RNA Polymerase I Promoter Clearance, Dual incision in TC-NER

Orthologs