PANTHER Gene Information

Gene Symbol(s):

Vnn1

Organism:

Mus musculus

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Gene Name:

Pantetheinase

Gene ID:

MGI:108395

Protein ID:

Q9Z0K8

Persistent Id:

PTN000064649

Alternate Ids:

AAH19203(EMBL-CDS)	BC019203(EMBL)
VNN1(Synonym)	Vnn1(Symbol)
ENSMUST00000041416(Ensembl_TRS)	CHEMBL4802063(ChEMBL)
22361(GeneID)	ENSMUSP00000040599(Ensembl_PRO)
VNN1_MOUSE(UniProtKB-ID)	MGI:108395(MGI)
NP_035834(refSeq)	Q9DCH8(AltAccession)
4138229(GI)	3.5.1.92 {ECO:0000269\|PubMed:11042271}(EC)
ENSMUSG00000037440(Ensembl)
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PANTHER Classification

PANTHER Family:	BIOTINIDASE-RELATED (PTHR10609)
PANTHER Subfamily:	PANTETHEINASE (PTHR10609:SF16)
PANTHER GO-slim Molecular Function:	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
PANTHER GO-slim Biological Process:	monocarboxylic acid metabolic process cellular modified amino acid metabolic process amide metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	hydrolase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GPI anchor binding, pantetheine hydrolase activity
GO BP Complete:	chronic inflammatory response, inflammatory response, positive regulation of T cell differentiation in thymus, acute inflammatory response, pantothenate metabolic process, innate immune response, coenzyme A catabolic process, positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway, cell-cell adhesion
GO CC Complete:	extracellular space, side of membrane, membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Immune System, Metabolism of vitamins and cofactors, Innate Immune System, Neutrophil degranulation, Post-translational modification: synthesis of GPI-anchored proteins, Metabolism, Vitamin B5 (pantothenate) metabolism, Metabolism of proteins, Post-translational protein modification, Metabolism of water-soluble vitamins and cofactors

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12705\|UniProtKB=O95497	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000018613.5\|UniProtKB=H2QTR5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004390.3\|UniProtKB=G3QP21	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000015089.4\|UniProtKB=A0A5F8A8E3	Macaca mulatta	LDO
RAT\|RGD=1310075\|UniProtKB=Q4KLZ0	Rattus norvegicus	LDO
BOVIN\|Gene=VNN1\|UniProtKB=Q58CQ9	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000015094.6\|UniProtKB=A0A140T891	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000004181.5\|UniProtKB=F1S3Q7	Sus scrofa	O
PIG\|Gene=VNN1\|UniProtKB=Q9BDJ5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022135.4\|UniProtKB=F6Z129	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000043054.2\|UniProtKB=A0A5F5XLV1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00805000995\|UniProtKB=Q9TSX8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017529.4\|UniProtKB=F6RTB1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005318.3\|UniProtKB=F7C4P1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010006816.1\|UniProtKB=A0A8V0XW73	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010004300.1\|UniProtKB=A0A8V0XM46	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010522.4\|UniProtKB=H9GGI6	Anolis carolinensis	LDO
XENLA\|Gene=LOC108705431\|UniProtKB=A0A310TMX5	Xenopus laevis	O
XENLA\|Gene=LOC108705439\|UniProtKB=A0A8J0U6X7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5471072\|UniProtKB=Q5M8L7	Xenopus tropicalis	LDO
BRAFL\|Gene=LOC118406135\|UniProtKB=A0A9J7KGH9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC575770\|UniProtKB=A0A7M7NQC0	Strongylocentrotus purpuratus	LDO
IXOSC\|EnsemblGenome=ISCW004822\|UniProtKB=B7PHC3	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g122468\|UniProtKB=A7SL86	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_33759\|UniProtKB=A9V7A5	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_8898\|UniProtKB=A9V1G4	Monosiga brevicollis	LDO
DICDI\|dictyBase=DDB_G0279675\|UniProtKB=Q54WG1	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_150765\|UniProtKB=F0ZH71	Dictyostelium purpureum	LDO