PANTHER Gene Information

Gene Symbol(s):

Nptn

Organism:

Mus musculus

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Gene Name:

Neuroplastin

Gene ID:

MGI:108077

Protein ID:

P97300

Persistent Id:

PTN000008514

Alternate Ids:

Q3U519(AltAccession)	SDR-1(Synonym)
Nptn(Symbol)	D50463(EMBL)
74150447(GI)	XM_006510882(refSeq)
BAC35855(EMBL-CDS)	ENSMUSG00000032336(Ensembl)
NPTN_MOUSE(UniProtKB-ID)	MGI:108077(MGI)
20320(GeneID)
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PANTHER Classification

PANTHER Family:	BASIGIN RELATED (PTHR10075)
PANTHER Subfamily:	NEUROPLASTIN (PTHR10075:SF108)
PANTHER GO-slim Molecular Function:	cell-cell adhesion mediator activity
PANTHER GO-slim Biological Process:	axon guidance cell recognition homophilic cell adhesion via plasma membrane adhesion molecules
PANTHER GO-slim Cellular Component:	axon plasma membrane
PANTHER protein class:	scaffold/adaptor protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein binding, cell-cell adhesion mediator activity, cell adhesion molecule binding, transmembrane transporter binding, type 1 fibroblast growth factor receptor binding
GO BP Complete:	synapse organization, positive regulation of long-term synaptic potentiation, excitatory synapse assembly, regulation of receptor localization to synapse, axon guidance, positive regulation of fibroblast growth factor receptor signaling pathway, visual learning, homophilic cell adhesion via plasma membrane adhesion molecules, intracellular calcium ion homeostasis, positive regulation of cytosolic calcium ion concentration, positive regulation of protein localization, dendrite self-avoidance, positive regulation of protein phosphorylation, positive regulation of ERK1 and ERK2 cascade, trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission, modulation of chemical synaptic transmission, positive regulation of neuron projection development, long-term synaptic potentiation, negative regulation of cytokine production, positive regulation of long-term neuronal synaptic plasticity
GO CC Complete:	presynaptic membrane, inhibitory synapse, postsynaptic density, presynaptic active zone membrane, synaptic membrane, plasma membrane, immunological synapse, cell surface, Schaffer collateral - CA1 synapse, GABA-ergic synapse, dendrite, glutamatergic synapse, axon, postsynaptic density membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17867\|UniProtKB=Q9Y639	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007260.6\|UniProtKB=H2Q9R9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000000742.4\|UniProtKB=G3QEN4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009869.4\|UniProtKB=I2CYK2	Macaca mulatta	LDO
RAT\|RGD=620296\|UniProtKB=P97546	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000008218.6\|UniProtKB=A0A3Q1LL79	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000001918.5\|UniProtKB=A0A8W4FIS6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000008148.4\|UniProtKB=A0A3Q2KVZ1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006343.5\|UniProtKB=M3W5R1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845027606.1\|UniProtKB=A0A8I3PYD1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000009865.4\|UniProtKB=A0A5F8GCP8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000001012.6\|UniProtKB=F6R9V8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010021642.1\|UniProtKB=F1NI46	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007192.4\|UniProtKB=H9GCE4	Anolis carolinensis	LDO
XENLA\|Gene=nptn.L\|UniProtKB=A0A1L8H008	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1011670\|UniProtKB=A0A6I8Q232	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000013168.2\|UniProtKB=H2MD66	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1821\|UniProtKB=Q6NZV3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014545.1\|UniProtKB=W5NB96	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007077.3\|UniProtKB=F6WVW2	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000006993.3\|UniProtKB=F6SBE5	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000013107.2\|UniProtKB=F7BNX3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000006931.3\|UniProtKB=F6VPC0	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_127723\|UniProtKB=C3YQA2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423600\|UniProtKB=A0A9J7LT12	Branchiostoma floridae	O
BRAFL\|Gene=LOC118404385\|UniProtKB=A0A9J7HGS2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423599\|UniProtKB=A0A9J7LT45	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC579970\|UniProtKB=A0A7M7SXW4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115919085\|UniProtKB=A0A7M7PU95	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888291\|UniProtKB=A0A7M7SXJ7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888739\|UniProtKB=A0A7M7PT21	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115917984\|UniProtKB=A0A7M7PNG4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918404\|UniProtKB=A0A7M7NC52	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105439348\|UniProtKB=A0A7M7NB82	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC589644\|UniProtKB=A0A7M7NXL6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC763963\|UniProtKB=A0A7M7PLI1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889062\|UniProtKB=A0A7M7N2U9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC579816\|UniProtKB=A0A7M7NDJ2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC587995\|UniProtKB=A0A7M7NC35	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105441352\|UniProtKB=A0A7M7N0N7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC591293\|UniProtKB=A0A7M7NFA6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889480\|UniProtKB=A0A7M7HLD6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC590851\|UniProtKB=A0A7M7PU83	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100893476\|UniProtKB=A0A7M7PK73	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC764448\|UniProtKB=A0A7M7N0N8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC590031\|UniProtKB=A0A7M7SV72	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105447552\|UniProtKB=A0A7M7NPI4	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00006978\|UniProtKB=G5EGI7	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00026617\|UniProtKB=A8WWW0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00100735\|UniProtKB=A0A2A6BMY4	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0261822\|UniProtKB=Q7KTJ7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008408\|UniProtKB=A0A1S4GYX2	Anopheles gambiae	O
CAEEL\|WormBase=WBGene00017184\|UniProtKB=Q8MQ86	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG08127\|UniProtKB=A8X5V7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00110202\|UniProtKB=A0A2A6D178	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004370\|UniProtKB=Q18806	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG10909\|UniProtKB=A8XC90	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00096413\|UniProtKB=A0A2A6BCQ6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00021305\|UniProtKB=Q9BPN5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG21818\|UniProtKB=A8Y0W1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00016354\|UniProtKB=H2KZ60	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00036696\|UniProtKB=A8XQ01	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG03355\|UniProtKB=A8WUU9	Caenorhabditis briggsae	O
CAEBR\|EnsemblGenome=WBGene00036697\|UniProtKB=A8XQ02	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG16045\|UniProtKB=A8XN78	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00109247\|UniProtKB=A0A2A6BJJ6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00116695\|UniProtKB=A0A2A6BHG7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0001257\|UniProtKB=Q09024	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP003141\|UniProtKB=Q7QBJ8	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_330310\|UniProtKB=E9HJ65	Daphnia pulex	O
DROME\|FlyBase=FBgn0037240\|UniProtKB=Q9VN14	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP000007\|UniProtKB=Q7QEI6	Anopheles gambiae	O
DROME\|FlyBase=FBgn0028482\|UniProtKB=Q9U4G1	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008943\|UniProtKB=A0A1S4GZP9	Anopheles gambiae	O
DROME\|FlyBase=FBgn0267728\|UniProtKB=Q7JXW8	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0004839\|UniProtKB=Q6AWJ9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029551\|UniProtKB=A0A453Z007	Anopheles gambiae	O
DROME\|FlyBase=FBgn0010473\|UniProtKB=Q967D7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007928\|UniProtKB=A0A1S4GWQ1	Anopheles gambiae	O
DROME\|FlyBase=FBgn0000635\|UniProtKB=P34082	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010245\|UniProtKB=A0A1S4H3F3	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP010969\|UniProtKB=A0A1S4H690	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP010970\|UniProtKB=A0A1S4H6D7	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP012226\|UniProtKB=A0A1S4H8Q1	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004993\|UniProtKB=A0A139WNR8	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031782\|UniProtKB=A0A139W9G1	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW020054\|UniProtKB=B7Q1Z8	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW016847\|UniProtKB=B7PAM8	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW000260\|UniProtKB=B7P249	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW017420\|UniProtKB=B7PCC8	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023928\|UniProtKB=B7QNJ6	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023403\|UniProtKB=B7QJ27	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW017597\|UniProtKB=B7PFS0	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW000259\|UniProtKB=B7P248	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW017602\|UniProtKB=B7PFS3	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW017407\|UniProtKB=B7PCC0	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW003491\|UniProtKB=B7PEB1	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW010083\|UniProtKB=B7PZR6	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG174821\|UniProtKB=T1F8I6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG97596\|UniProtKB=T1G9H8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG89107\|UniProtKB=T1G788	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g201761\|UniProtKB=A7RT57	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246644\|UniProtKB=A7SPS1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215547\|UniProtKB=A7SPS5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g225835\|UniProtKB=A8DVX3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246645\|UniProtKB=A7SPS4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g210858\|UniProtKB=A7SE48	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g4493\|UniProtKB=A7TCD9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g221265\|UniProtKB=A7T289	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g134128\|UniProtKB=A7SVH6	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g80686\|UniProtKB=A7RGL8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g50586\|UniProtKB=A7RT26	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g80596\|UniProtKB=A7RGM0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g205787\|UniProtKB=A7S2I3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g384\|UniProtKB=A7SVH4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g41698\|UniProtKB=A7SSL0	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG59150\|UniProtKB=B3S4N4	Trichoplax adhaerens	O