PANTHER Gene Information

Gene Symbol(s):

Adam7

Organism:

Mus musculus

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Gene Name:

Disintegrin and metalloproteinase domain-containing protein 7

Gene ID:

MGI:107247

Protein ID:

O35227

Persistent Id:

PTN000225396

Alternate Ids:

MGI:107247(MGI)	2465568(GI)
ADAM7_MOUSE(UniProtKB-ID)	NP_031428(refSeq)
AC154706(EMBL)	F8VQC6(AltAccession)
11500(GeneID)	AAC53368(EMBL-CDS)
ADAM 7(Synonym)	ENSMUSP00000022640(Ensembl_PRO)
ENSMUST00000022640(Ensembl_TRS)	Adam7{ECO:0000312\|MGI:MGI:107247}(Symbol)
ENSMUSG00000022056(Ensembl)
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PANTHER Classification

PANTHER Family:	ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN (PTHR11905)
PANTHER Subfamily:	DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 7 (PTHR11905:SF21)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	metalloprotease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protein binding, endopeptidase activity, metalloendopeptidase activity
GO BP Complete:	positive regulation of sperm capacitation, proteolysis, epithelial cell morphogenesis, epididymis development, positive regulation of flagellated sperm motility
GO CC Complete:	apical part of cell, plasma membrane, cell surface

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=214\|UniProtKB=Q9H2U9	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020086.7\|UniProtKB=H2R9W0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001012.3\|UniProtKB=G3SD01	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000007909.4\|UniProtKB=F6PRG1	Macaca mulatta	LDO
RAT\|RGD=62032\|UniProtKB=Q63180	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000039171.4\|UniProtKB=F1MRA8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000009646.4\|UniProtKB=A0A5G2QIN7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020537.4\|UniProtKB=A0A3Q2GXG2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013087.6\|UniProtKB=A0A5F5Y014	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014694.1\|UniProtKB=A0A8I3NRQ4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016755.4\|UniProtKB=A0A5F8GKI8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000008021.2\|UniProtKB=A0A6I8MY00	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010019012.1\|UniProtKB=A0A8V0ZFU0	Gallus gallus	O
XENLA\|Gene=LOC108705558\|UniProtKB=A0A8J1MJH0	Xenopus laevis	O
XENLA\|Gene=adam28.3.S\|UniProtKB=A0A8J0UN56	Xenopus laevis	O
XENTR\|Gene=adam28.4\|UniProtKB=A0A8J1JAN5	Xenopus tropicalis	O
XENTR\|Gene=adam28.3\|UniProtKB=A0A8J1JET8	Xenopus tropicalis	O
XENLA\|Gene=adam28.2.L\|UniProtKB=A0A8J1MIE9	Xenopus laevis	O
XENLA\|Gene=adam28.2.S\|UniProtKB=A0A8J0UUT5	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5949648\|UniProtKB=B1H325	Xenopus tropicalis	O
XENLA\|Gene=adam28.1l.L\|UniProtKB=B1H1S1	Xenopus laevis	O
XENLA\|Gene=adam28.1.S\|UniProtKB=A0A8J0UP88	Xenopus laevis	O
XENLA\|Gene=adam28.1.L\|UniProtKB=A0A1L8H1T7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-982024\|UniProtKB=E2ICM2	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000016155.2\|UniProtKB=A0A3B3I3J7	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000015430.1\|UniProtKB=W5NED3	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000015424.1\|UniProtKB=W5NEC7	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000020992.1\|UniProtKB=H2XTH9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005135.3\|UniProtKB=F6VBC2	Ciona intestinalis	O
BRAFL\|Gene=LOC118412902\|UniProtKB=A0A9J7MLP7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118412901\|UniProtKB=A0A9J7MLQ0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC105442236\|UniProtKB=A0A7M7PLA1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105439308\|UniProtKB=A0A7M7P4U2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC756811\|UniProtKB=A0A7M7NUR4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100892132\|UniProtKB=A0A7M7NKQ2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC373195\|UniProtKB=A0A7M6UT16	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00016423\|UniProtKB=Q9N5X7	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00035232\|UniProtKB=A8XKT8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00115825\|UniProtKB=A0A2A6BF50	Pristionchus pacificus	O
HELRO\|EnsemblGenome=HelroG191849\|UniProtKB=T1FTC5	helobdella robusta	O
CAEEL\|WormBase=WBGene00006804\|UniProtKB=G5EFD5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG15766\|UniProtKB=A8XMR2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00109478\|UniProtKB=A0A2A6BAU0	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00270320\|UniProtKB=A0A1D3PCM0	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00017865\|UniProtKB=Q19844	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16757\|UniProtKB=A8XPR5	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00000074\|UniProtKB=G5EDW5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG07388\|UniProtKB=A8X4V8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00280621\|UniProtKB=A0A2A6C198	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00092388\|UniProtKB=A0A2A6B8B3	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00273278\|UniProtKB=A0A2A6C8W9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277995\|UniProtKB=A0A2A6BC51	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0034903\|UniProtKB=B7YZP6	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029515\|UniProtKB=A0A453Z0T3	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC033716\|UniProtKB=A0A139WEF8	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_189791\|UniProtKB=E9FRL1	Daphnia pulex	O
DROME\|FlyBase=FBgn0259110\|UniProtKB=X2JE21	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP000974\|UniProtKB=A0A903WTW0	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC034399\|UniProtKB=A0A139WBK0	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_45366\|UniProtKB=E9G3K5	Daphnia pulex	O
DROME\|FlyBase=FBgn0265140\|UniProtKB=Q6QU65	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP013468\|UniProtKB=A0A1S4HDE7	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP003496\|UniProtKB=A0A1S4GIU0	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP003498\|UniProtKB=A0A1S4GI55	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC010657\|UniProtKB=D6X2H8	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_316505\|UniProtKB=E9GD49	Daphnia pulex	O
DAPPU\|Gene_ORFName=DAPPUDRAFT_56831\|UniProtKB=E9H0Q2	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW000564\|UniProtKB=B7P2V7	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW011231\|UniProtKB=B7Q4I3	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023638\|UniProtKB=B7QM92	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW001157\|UniProtKB=B7P187	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW006692\|UniProtKB=B7PPE9	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW006669\|UniProtKB=B7PR96	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW008968\|UniProtKB=B7Q2B8	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW010536\|UniProtKB=B7Q897	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW001423\|UniProtKB=B7P4M8	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG163021\|UniProtKB=T1ETK9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG194811\|UniProtKB=T1FWF8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG105422\|UniProtKB=T1EDU7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG159200\|UniProtKB=T1ENQ6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG99722\|UniProtKB=T1G9U7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG177813\|UniProtKB=T1FCB1	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG187950\|UniProtKB=T1FPI0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG172909\|UniProtKB=T1F643	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG194516\|UniProtKB=T1FW53	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG192899\|UniProtKB=T1FUE3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG96397\|UniProtKB=T1G9B8	helobdella robusta	O
TRIAD\|EnsemblGenome=TriadG64349\|UniProtKB=B3SAV4	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG32380\|UniProtKB=B3SAV3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG32386\|UniProtKB=B3SAW2	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG32445\|UniProtKB=B3SAV6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG61393\|UniProtKB=B3SAV5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG1282\|UniProtKB=B3RIV5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG62011\|UniProtKB=B3SCL1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG32362\|UniProtKB=B3SAV2	Trichoplax adhaerens	O
YARLI\|EnsemblGenome=YALI0_E05423g\|UniProtKB=Q6C6X8	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_02810\|UniProtKB=C8VJI7	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G14420\|UniProtKB=E9R9I7	Neosartorya fumigata	O
EMENI\|EnsemblGenome=ANIA_05619\|UniProtKB=Q5B1G1	Emericella nidulans	O
ASPFU\|Gene_ORFName=AFUA_4G11150\|UniProtKB=Q4WQ08	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU06834\|UniProtKB=Q7SCH0	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_15649\|UniProtKB=Q0TY27	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC17A5.04c\|UniProtKB=O13766	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01321\|UniProtKB=B6K0C7	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNK03040\|UniProtKB=Q5K965	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNI00310\|UniProtKB=Q5KC43	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_02711\|UniProtKB=A0A0D1E0I2	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_12183\|UniProtKB=E3KPJ2	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_16536\|UniProtKB=F4P1Z6	Batrachochytrium dendrobatidis	O