PANTHER Gene Information

Gene Symbol(s):

Efna3

Organism:

Mus musculus

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Gene Name:

Ephrin-A3

Gene ID:

MGI:106644

Protein ID:

O08545

Persistent Id:

PTN000139218

Alternate Ids:

EFNA3_MOUSE(UniProtKB-ID)	2843099(GI)
NM_010108(refSeq)	MGI:106644(MGI)
EFNA3(Synonym)	Q08AV0(AltAccession)
Efna3(Symbol)	AAC39961(EMBL-CDS)
BC107002(EMBL)	ENSMUST00000029673(Ensembl_TRS)
13638(GeneID)	ENSMUSP00000029673(Ensembl_PRO)
ENSMUSG00000028039(Ensembl)
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PANTHER Classification

PANTHER Family:	EPHRIN (PTHR11304)
PANTHER Subfamily:	EPHRIN-A3 (PTHR11304:SF5)
PANTHER GO-slim Molecular Function:	signaling receptor binding
PANTHER GO-slim Biological Process:	axon guidance transmembrane receptor protein tyrosine kinase signaling pathway
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	membrane-bound signaling molecule

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ephrin receptor binding
GO BP Complete:	negative regulation of angiogenesis, ephrin receptor signaling pathway, axon guidance, positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process, regulation of neuron differentiation
GO CC Complete:	side of membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Nervous system development, Axon guidance, EPHA-mediated growth cone collapse, EPH-Ephrin signaling, EPH-ephrin mediated repulsion of cells, Developmental Biology

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3223\|UniProtKB=P52797	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001406.5\|UniProtKB=H2Q066	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013918.3\|UniProtKB=G3RDG8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000023350.4\|UniProtKB=I2CYI5	Macaca mulatta	LDO
BOVIN\|Ensembl=ENSBTAG00000033423.4\|UniProtKB=F1N163	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000006531.4\|UniProtKB=F1RGQ3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022186.4\|UniProtKB=F6Z1K6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005288.6\|UniProtKB=A0A337ST16	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013487.1\|UniProtKB=A0A8I3NEL5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017112.4\|UniProtKB=F7B5C7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000048551.1\|UniProtKB=A0A6I8P9X8	Ornithorhynchus anatinus	LDO
XENLA\|Gene=efna3.S\|UniProtKB=Q7SY61	Xenopus laevis	O
XENLA\|Gene=efna3.L\|UniProtKB=A0A1L8FDG3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5720826\|UniProtKB=Q5M7P3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000027127.1\|UniProtKB=A0A3B3H8K1	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060503-186\|UniProtKB=A0A8M1Q1X6	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000028633.1\|UniProtKB=A0A3B3IGE1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-011108-1\|UniProtKB=Q90YC5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006835.1\|UniProtKB=W5MIQ6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005718.3\|UniProtKB=F6U2Y7	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000010080.3\|UniProtKB=Q4H3M1	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005716.3\|UniProtKB=F6WPE8	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005717.3\|UniProtKB=F6U302	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000010012.3\|UniProtKB=Q4H3L8	Ciona intestinalis	O
BRAFL\|Gene=LOC118411608\|UniProtKB=A0A9J7MJV8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411210\|UniProtKB=A0A9J7KRI4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426872\|UniProtKB=A0A9J7N752	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC763882\|UniProtKB=A0A7M7PC46	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115927222\|UniProtKB=A0A7M7PBC7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00006869\|UniProtKB=G5EEE7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG10748\|UniProtKB=A8XBQ1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00117869\|UniProtKB=A0A2A6B6J7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00001165\|UniProtKB=O44516	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024824\|UniProtKB=Q624D2	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00001164\|UniProtKB=Q19475	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG07443\|UniProtKB=A8X4R5	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00001163\|UniProtKB=Q9U3M2	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00027088\|UniProtKB=A8WXH5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00104419\|UniProtKB=A0A2A6BDS0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00094625\|UniProtKB=A0A2A6CBI1	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0040324\|UniProtKB=Q9V4E1	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009426\|UniProtKB=Q5TXC6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008794\|UniProtKB=D6WRM8	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC004127\|UniProtKB=D6W6N4	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_308080\|UniProtKB=E9H642	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW018996\|UniProtKB=B7PNC7	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG177176\|UniProtKB=T1FBB7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG194703\|UniProtKB=T1FWC1	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG169042\|UniProtKB=T1F1A9	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g236436\|UniProtKB=A7RL54	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g212995\|UniProtKB=A7SIY5	Nematostella vectensis	O