PANTHER Gene Information

Gene Symbol(s):

Six5

Organism:

Mus musculus

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Gene Name:

Homeobox protein SIX5

Gene ID:

MGI:106220

Protein ID:

P70178

Persistent Id:

PTN000044449

Alternate Ids:

Sine oculis homeobox homolog 5(Synonym)	ENSMUSP00000045973(Ensembl_PRO)
BAA11824(EMBL-CDS)	ENSMUSG00000040841(Ensembl)
Six5(Symbol)	D83146(EMBL)
SIX5_MOUSE(UniProtKB-ID)	ENSMUST00000049454(Ensembl_TRS)
1542813(GI)	NM_011383(refSeq)
20475(GeneID)	MGI:106220(MGI)
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PANTHER Classification

PANTHER Family:	HOMEOBOX PROTEIN SIX (PTHR10390)
PANTHER Subfamily:	HOMEOBOX PROTEIN SIX5 (PTHR10390:SF40)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	transcription regulator complex nucleus
PANTHER protein class:	homeodomain transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	cell population proliferation, negative regulation of DNA-templated transcription, spermatid development, negative regulation of cell population proliferation, lens development in camera-type eye, positive regulation of transcription by RNA polymerase II, Leydig cell proliferation, negative regulation of skeletal muscle satellite cell proliferation, regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus, transcription regulator complex, intracellular membrane-bounded organelle, cytosol, Golgi apparatus, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10891\|UniProtKB=Q8N196	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000033681.2\|UniProtKB=H2R5Z8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007958.3\|UniProtKB=G3SBS4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000051573.1\|UniProtKB=A0A5F8AMB5	Macaca mulatta	LDO
RAT\|RGD=1305040\|UniProtKB=A0A0G2K7K3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000013346.5\|UniProtKB=E1BAD7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000035791.3\|UniProtKB=A0A287ANB9	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000030970.4\|UniProtKB=M3X906	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004815.1\|UniProtKB=A0A8I3RSA9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000041693.1\|UniProtKB=A0A5F8GNT6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000050748.1\|UniProtKB=A0A6I8PIR0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010017918.1\|UniProtKB=A0A8V0YXE0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000006593.3\|UniProtKB=H9GBN0	Anolis carolinensis	O
XENLA\|Gene=six4.S\|UniProtKB=A0A1L8F006	Xenopus laevis	O
XENLA\|Gene=six4.L\|UniProtKB=A0A8J0TK91	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-481699\|UniProtKB=F6Y0Z9	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000006762.2\|UniProtKB=H2LQZ2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-010201-3\|UniProtKB=Q9DEC0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014840.1\|UniProtKB=W5NCB5	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000015756.2\|UniProtKB=H2MLZ5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-010201-2\|UniProtKB=A4IG26	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-010201-1\|UniProtKB=Q9DEE7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010093.1\|UniProtKB=W5MVE0	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000004748.3\|UniProtKB=F6PRL5	Ciona intestinalis	O
BRAFL\|Gene=LOC118420459\|UniProtKB=A0A9J7LIN4	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC105438007\|UniProtKB=A0A7M7T0I7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC576184\|UniProtKB=A0A7M7RA28	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00006775\|UniProtKB=O17894	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00027265\|UniProtKB=A8WY36	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00276125\|UniProtKB=A0A2A6CSJ9	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0027364\|UniProtKB=Q9Y1P6	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP011065\|UniProtKB=A0A1S4H6N6	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP011067\|UniProtKB=A0A1S4H5P0	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003852\|UniProtKB=D6WFW3	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_27769\|UniProtKB=E9FYU0	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW023235\|UniProtKB=B7QJ38	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g56637\|UniProtKB=A7SS98	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g138693\|UniProtKB=A7SZ27	Nematostella vectensis	O
DICDI\|dictyBase=DDB_G0272967\|UniProtKB=Q86IH1	Dictyostelium discoideum	O
AMBTC\|EnsemblGenome=AMTR_s00092p00109950\|UniProtKB=W1NUF7	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_458G00060\|UniProtKB=A0A0K9P0N3	Zostera marina	O
MUSAM\|EnsemblGenome=Ma06_g23650\|UniProtKB=A0A804JJL6	Musa acuminata subsp. malaccensis	O
BRADI\|EnsemblGenome=BRADI_4g03303v3\|UniProtKB=A0A2K2CK81	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0116070\|UniProtKB=A0A8I6WL30	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS3B02G131700\|UniProtKB=A0A3B6FI33	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G112300\|UniProtKB=A0A3B6ED19	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G114300\|UniProtKB=A0A3B6GNY6	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0237550\|UniProtKB=A0A8I6XK40	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2B02G147300\|UniProtKB=A0A3B6C0Z6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G124800\|UniProtKB=A0A3B6ATD3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G127700\|UniProtKB=A0A3B6D7Z3	Triticum aestivum	O
SPIOL\|Gene=LOC110805428\|UniProtKB=A0A9R0KCM9	Spinacia oleracea	O
HELAN\|Gene_ORFName=HannXRQ_Chr07g0200581\|UniProtKB=A0A251UEC2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0659971\|UniProtKB=A0A251SLF5	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C200089500\|UniProtKB=A0A9R1W8T6	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a000669mg\|UniProtKB=A0A022PWI5	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_29815\|UniProtKB=A0A1U8F663	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400000999\|UniProtKB=M0ZKD0	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc11g006200.2\|UniProtKB=A0A3Q7INY6	Solanum lycopersicum	O
TOBAC\|Gene=LOC107793383\|UniProtKB=A0A1S4A3P7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107766955\|UniProtKB=A0A1S3XNE8	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi11g00961\|UniProtKB=F6H9M0	Vitis vinifera	O
VITVI\|Gene_OrderedLocusName=VIT_07s0005g06050\|UniProtKB=F6HZZ5	Vitis vinifera	O
VITVI\|Gene_OrderedLocusName=VIT_19s0085g00350\|UniProtKB=F6H9W6	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_K01361\|UniProtKB=A0A059A2P3	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00003017001\|UniProtKB=A0A078IJL3	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00030122001\|UniProtKB=A0A078JAD7	Brassica napus	O
BRACM\|EnsemblGenome=Bra014277\|UniProtKB=M4DCR0	Brassica campestris	O
ARATH\|Gene_OrderedLocusName=At4g12750\|UniProtKB=F4JRF5	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107923916\|UniProtKB=A0A1U8L4N9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107912490\|UniProtKB=A0A1U8K0X1	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_002532\|UniProtKB=A0A061DLH8	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g001088mg\|UniProtKB=A0A067EIJ0	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_014G173300v3\|UniProtKB=A0A2K1XXE1	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_014G197800v3\|UniProtKB=A0A2K1XYM7	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_12G058700\|UniProtKB=A0A2C9UTP9	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1211540\|UniProtKB=B9SF03	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_05G221500\|UniProtKB=K7KRT9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G028000\|UniProtKB=K7L4N1	Glycine max	O
CUCSA\|EnsemblGenome=Csa_7G270590\|UniProtKB=A0A0A0K3U2	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G029400\|UniProtKB=A0A251PUE5	Prunus persica	O