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Gene Symbol(s):
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Ptk2b
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| Organism: |
Mus musculus |
| View Gene in Tree |
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| Gene Name: |
Protein-tyrosine kinase 2-beta
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| Gene ID: |
MGI:104908
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| Protein ID: |
Q9QVP9
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| Persistent Id: |
PTN000700537 |
| Alternate Ids: |
| XP_006518789(refSeq) |
Proline-rich tyrosine kinase 2(Synonym) |
| 755547986(GI) |
2.7.10.2(EC) |
| AAI44850(EMBL-CDS) |
BC137704(EMBL) |
| ENSMUST00000022622(Ensembl_TRS) |
CHEMBL1075289(ChEMBL) |
| Ptk2b(Symbol) |
ENSMUSP00000137008(Ensembl_PRO) |
| 19229(GeneID) |
ENSMUSG00000059456(Ensembl) |
| G3X8V1(AltAccession) |
FAK2_MOUSE(UniProtKB-ID) |
MGI:104908(MGI) |
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Show All
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| GO MF Complete: |
ATP binding, glutamate receptor binding, protein binding, ubiquitin protein ligase binding, non-membrane spanning protein tyrosine kinase activity, neurotransmitter receptor regulator activity, protein kinase activity, calcium/calmodulin-dependent protein kinase activity, 3-phosphoinositide-dependent protein kinase binding, enzyme binding, protein-containing complex binding
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| GO BP Complete: |
activation of Janus kinase activity, signal complex assembly, peptidyl-tyrosine phosphorylation, positive regulation of translation, cytoskeleton organization, epidermal growth factor receptor signaling pathway, sprouting angiogenesis, actin filament organization, regulation of postsynaptic density assembly, negative regulation of potassium ion transport, stress fiber assembly, positive regulation of angiogenesis, negative regulation of bone mineralization, cortical cytoskeleton organization, positive regulation of protein metabolic process, response to glucose, positive regulation of cell growth, response to hypoxia, marginal zone B cell differentiation, bone resorption, cellular response to fluid shear stress, positive regulation of neuron projection development, long-term synaptic potentiation, negative regulation of muscle cell apoptotic process, positive regulation of synaptic transmission, glutamatergic, long-term synaptic depression, ionotropic glutamate receptor signaling pathway, focal adhesion assembly, response to cocaine, adaptive immune response, response to hydrogen peroxide, response to cation stress, response to hormone, cellular defense response, tumor necrosis factor-mediated signaling pathway, vascular endothelial growth factor receptor signaling pathway, oocyte maturation, regulation of actin cytoskeleton organization, positive regulation of cell-matrix adhesion, positive regulation of protein kinase activity, response to immobilization stress, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, positive regulation of cell migration, regulation of cell shape, positive regulation of ubiquitin-dependent protein catabolic process, positive regulation of nitric oxide biosynthetic process, activation of GTPase activity, Golgi organization, negative regulation of cell population proliferation, positive regulation of cell population proliferation, response to cAMP, cell adhesion, postsynaptic modulation of chemical synaptic transmission, response to xenobiotic stimulus, protein phosphorylation, response to mechanical stimulus, negative regulation of neuron apoptotic process, MAPK cascade, response to ethanol, neuron migration, integrin-mediated signaling pathway, response to ischemia, regulation of macrophage chemotaxis, angiogenesis, positive regulation of B cell chemotaxis, regulation of ubiquitin-dependent protein catabolic process, positive regulation of endothelial cell migration, positive regulation of DNA biosynthetic process, positive regulation of reactive oxygen species metabolic process, negative regulation of myeloid cell differentiation, endothelin receptor signaling pathway, neuron projection development, peptidyl-tyrosine autophosphorylation, cell surface receptor signaling pathway, blood vessel endothelial cell migration, positive regulation of cytosolic calcium ion concentration, regulation of release of sequestered calcium ion into cytosol, cellular response to retinoic acid, negative regulation of apoptotic process, positive regulation of JNK cascade, response to calcium ion, chemokine-mediated signaling pathway, positive regulation of actin filament polymerization, positive regulation of ERK1 and ERK2 cascade, positive regulation of excitatory postsynaptic potential, glial cell proliferation, regulation of cell adhesion, negative regulation of ossification
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| GO CC Complete: |
postsynaptic density, postsynaptic density, intracellular component, neuronal cell body, cell projection, plasma membrane, growth cone, Schaffer collateral - CA1 synapse, nucleus, dendrite, apical dendrite, presynapse, cytoskeleton, perinuclear region of cytoplasm, postsynapse, focal adhesion, cell cortex, dendritic spine, cell body, NMDA selective glutamate receptor complex, glutamatergic synapse, axon, lamellipodium
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| Reactome Pathways: |
Signaling by Receptor Tyrosine Kinases, Interleukin-2 family signaling, Immune System, Signaling by VEGF, Signaling by Rho GTPases, Signal Transduction, VEGFA-VEGFR2 Pathway, RHOU GTPase cycle, Interleukin-2 signaling, Signal regulatory protein family interactions, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Signaling by Interleukins, RHO GTPase cycle, Cytokine Signaling in Immune system, Cell-Cell communication
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