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Gene Symbol(s):
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Cdk5
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| Organism: |
Mus musculus |
| View Gene in Tree |
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| Gene Name: |
Cyclin-dependent kinase 5
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| Gene ID: |
MGI:101765
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| Protein ID: |
P49615
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| Persistent Id: |
PTN000623869 |
| Alternate Ids: |
| 12568(GeneID) |
547568(GI) |
| CHEMBL3885555(ChEMBL) |
ENSMUSP00000030814(Ensembl_PRO) |
| Cdk5{ECO:0000312|MGI:MGI:101765}(Symbol) |
Cell division protein kinase 5 {ECO:0000305}(Synonym) |
| D29678(EMBL) |
ENSMUST00000030814(Ensembl_TRS) |
| MGI:101765(MGI) |
BAA06148(EMBL-CDS) |
| CDK5_MOUSE(UniProtKB-ID) |
ENSMUSG00000028969(Ensembl) |
| 2.7.11.1(EC) |
NP_031694(refSeq) |
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Show All
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| GO MF Complete: |
ErbB-2 class receptor binding, ephrin receptor binding, ErbB-3 class receptor binding, ribosomal protein S6 kinase activity, DNA-dependent protein kinase activity, ATP binding, histone H2AT120 kinase activity, p53 binding, acetylcholine receptor activator activity, AMP-activated protein kinase activity, histone H3S57 kinase activity, histone H4S1 kinase activity, histone H3S28 kinase activity, histone H3T45 kinase activity, histone H2AXS139 kinase activity, protein serine kinase activity, protein kinase binding, histone kinase activity, histone H3S10 kinase activity, histone H2BS14 kinase activity, histone H2AS1 kinase activity, protein kinase activity, eukaryotic translation initiation factor 2alpha kinase activity, cyclin-dependent protein serine/threonine kinase activity, protein serine/threonine kinase activity, 3-phosphoinositide-dependent protein kinase activity, protein binding, histone H2AS121 kinase activity, histone H3T3 kinase activity, histone H2BS36 kinase activity, Hsp90 protein binding, cytoskeletal protein binding, Rho-dependent protein serine/threonine kinase activity, kinase activity, histone H3T11 kinase activity, histone H3T6 kinase activity
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| GO BP Complete: |
positive regulation of protein binding, positive regulation of glial cell apoptotic process, visual learning, central nervous system neuron development, intracellular protein transport, associative learning, regulation of cell cycle phase transition, exocytosis, cortical actin cytoskeleton organization, nucleocytoplasmic transport, receptor catabolic process, forebrain development, negative regulation of DNA-templated transcription, synaptic vesicle transport, synaptic vesicle endocytosis, axonogenesis, negative regulation of synaptic plasticity, apoptotic process, regulated exocytosis, regulation of synaptic plasticity, negative regulation of protein ubiquitination, establishment of localization in cell, regulation of synaptic transmission, glutamatergic, neuron apoptotic process, regulation of presynaptic cytosolic calcium ion concentration, regulation of dendritic spine morphogenesis, regulation of postsynaptic membrane potential, negative regulation of protein export from nucleus, excitatory postsynaptic potential, cerebellum development, neuron differentiation, response to cocaine, cerebral cortex development, receptor clustering, DNA damage response, serine phosphorylation of STAT protein, corpus callosum development, synapse assembly, positive regulation of protein kinase activity, sensory perception of pain, peptidyl-serine phosphorylation, regulation of cell migration, peptidyl-threonine phosphorylation, calcium ion import, layer formation in cerebral cortex, positive regulation of protein targeting to membrane, motor neuron axon guidance, Schwann cell development, telencephalon development, negative regulation of cell cycle, neuron projection morphogenesis, negative regulation of proteolysis, protein phosphorylation, regulation of synapse pruning, cerebellar cortex development, positive regulation of neuron apoptotic process, cerebellar cortex formation, dendrite morphogenesis, cell division, neuron migration, chromatin remodeling, synaptic transmission, dopaminergic, behavioral response to cocaine, phosphorylation, protein localization to synapse, cell migration, cell-matrix adhesion, regulation of protein localization to plasma membrane, oligodendrocyte differentiation, neuron projection development, cellular response to amyloid-beta, hippocampus development, positive regulation of calcium ion-dependent exocytosis, mitochondrion organization, positive regulation of presynaptic cytosolic calcium concentration, rhythmic process, negative regulation of axon extension, skeletal muscle tissue development, positive regulation of protein phosphorylation, synaptic transmission, glutamatergic
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| GO CC Complete: |
postsynaptic density, cyclin-dependent protein kinase holoenzyme complex, neuronal cell body, perikaryon, neuron projection, plasma membrane, nucleoplasm, microtubule, growth cone, Schaffer collateral - CA1 synapse, nucleus, dendrite, presynapse, postsynapse, cytoplasm, membrane, cytosol, cell junction, filopodium, neuromuscular junction, glutamatergic synapse, protein kinase 5 complex, axon, lamellipodium
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| Reactome Pathways: |
Regulation of TP53 Activity through Phosphorylation, Nervous system development, G alpha (i) signalling events, Signal Transduction, Axon guidance, Generic Transcription Pathway, GPCR downstream signalling, Gene expression (Transcription), DARPP-32 events, Semaphorin interactions, CRMPs in Sema3A signaling, Regulation of TP53 Activity, Transcriptional Regulation by TP53, Signaling by GPCR, Opioid Signalling, Developmental Biology, RNA Polymerase II Transcription
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