PANTHER Gene Information

Gene Symbol(s):

Mettl6

Organism:

Rattus norvegicus

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Gene Name:

tRNA N(3)-methylcytidine methyltransferase METTL6

Gene ID:

1359565

Protein ID:

Q6AXU8

Persistent Id:

PTN000516312

Alternate Ids:

AAH79309(EMBL-CDS)	81910851(GI)
ENSRNOT00000084645(Ensembl_TRS)	BC079309(EMBL)
METL6(Synonym)	Mettl6(Symbol)
ENSRNOP00000074466(Ensembl_PRO)	1359565(RGD)
NM_001007623(refSeq)	290564(GeneID)
2.1.1.- {ECO:0000250\|UniProtKB:Q8BVH9}(EC)	METL6_RAT(UniProtKB-ID)
ENSRNOG00000052391(Ensembl)
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PANTHER Classification

PANTHER Family:	METHYLTRANSFERASE-RELATED (PTHR22809)
PANTHER Subfamily:	TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL6 (PTHR22809:SF5)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	methyltransferase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	RNA methyltransferase activity, guanyl-nucleotide exchange factor activity, SH3 domain binding, S-adenosylmethionine-dependent methyltransferase activity, tRNA (cytidine-3-)-methyltransferase activity, enzyme binding
GO BP Complete:	tRNA processing, tRNA methylation, tRNA modification, intracellular signal transduction, methylation
GO CC Complete:	nucleus, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=28343\|UniProtKB=Q8TCB7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000030297.5\|UniProtKB=A0A2I3RDB8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000024436.2\|UniProtKB=A0A2I2Z1U9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000004933.4\|UniProtKB=G7MJV8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1914261\|UniProtKB=Q8BVH9	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000023375.4\|UniProtKB=E1BIG0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005035949.1\|UniProtKB=A0A8D0RMK9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000055054.1\|UniProtKB=F6QR92	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000022284.4\|UniProtKB=M3WTU3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004810.1\|UniProtKB=A0A8I3MRG8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014536.3\|UniProtKB=F7E9G8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000006755.4\|UniProtKB=A0A6I8NDH7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010016917.1\|UniProtKB=A0A8V0YYD4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002806.4\|UniProtKB=G1KB69	Anolis carolinensis	LDO
XENLA\|Gene=mettl6.S\|UniProtKB=A0A1L8FRJ4	Xenopus laevis	O
XENLA\|Gene=mettl6.L\|UniProtKB=A0A1L8FWG2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5809155\|UniProtKB=A4IJ22	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015510.2\|UniProtKB=H2ML52	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-926\|UniProtKB=Q6NY40	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001835.1\|UniProtKB=W5M191	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007345.3\|UniProtKB=F6XYB7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118424065\|UniProtKB=A0A9J7LSF9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC589679\|UniProtKB=A0A7M7RH65	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00014205\|UniProtKB=Q23383	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00026432\|UniProtKB=A8WVF2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00305204\|UniProtKB=A0A8R1Z4U6	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0085224\|UniProtKB=A1ZAY5	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP029587\|UniProtKB=A0A453Z0V4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC004823\|UniProtKB=D6WB49	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_126903\|UniProtKB=E9FW77	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW021394\|UniProtKB=B7Q696	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG71342\|UniProtKB=T1G0J9	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g234398\|UniProtKB=A7RRX4	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG22960\|UniProtKB=B3RQN2	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_23351\|UniProtKB=A9UT49	Monosiga brevicollis	LDO
SCHPO\|PomBase=SPBC3H7.11\|UniProtKB=O74386	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04453\|UniProtKB=B6K6V3	Schizosaccharomyces japonicus	LDO
USTMA\|EnsemblGenome=UMAG_11792\|UniProtKB=A0A0D1CI17	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_90104\|UniProtKB=F4P6Y2	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=EHI_069570\|UniProtKB=C4LWP5	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0274197\|UniProtKB=Q8T199	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_83855\|UniProtKB=F1A0U5	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_21_0020\|UniProtKB=Q4QCL7	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.70.6040\|UniProtKB=Q38C62	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_9528\|UniProtKB=A8B4L5	Giardia intestinalis	O
CHLRE\|EnsemblGenome=CHLRE_16g668100v5\|UniProtKB=A0A2K3CUF5	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00009p00189830\|UniProtKB=W1NI87	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_1G03320\|UniProtKB=A0A0K9PQ33	Zostera marina	O
MUSAM\|EnsemblGenome=Ma05_g13150\|UniProtKB=A0A804J3X6	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_032944mg\|UniProtKB=K4A247	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G116500\|UniProtKB=C5X4E1	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb305860\|UniProtKB=B4FY91	Zea mays	O
ORYSJ\|EnsemblGenome=Os07g0414200\|UniProtKB=Q7EYV5	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_5g05210v3\|UniProtKB=A0A0Q3I7K4	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0669630\|UniProtKB=A0A8I6YDN4	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS7B02G110800\|UniProtKB=A0A3B6SEG3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G206900\|UniProtKB=A0A3B6TGQ6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G203800\|UniProtKB=A0A3B6RCA6	Triticum aestivum	O
NELNU\|Gene=LOC104610070\|UniProtKB=A0A1U8B5U3	Nelumbo nucifera	O
SPIOL\|Gene=LOC110799690\|UniProtKB=A0A9R0J666	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr07g0301191\|UniProtKB=A0A251T7X9	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C200089550\|UniProtKB=A0A9R1XWR5	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a009894mg\|UniProtKB=A0A022QYZ2	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_29819\|UniProtKB=A0A2G2Y6N0	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc11g006130.2\|UniProtKB=A0A3Q7IPF5	Solanum lycopersicum	O
TOBAC\|Gene=LOC107767130\|UniProtKB=A0A1S3XNP9	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi14g00551\|UniProtKB=F6HVI1	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_B02134\|UniProtKB=A0A059D4D7	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00089370001\|UniProtKB=A0A078IEC2	Brassica napus	O
BRACM\|EnsemblGenome=Bra021334\|UniProtKB=M4DXT8	Brassica campestris	O
ARATH\|TAIR=locus=2199529\|UniProtKB=A0A1P8AUR3	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107889244\|UniProtKB=A0A1U8HSY8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107926812\|UniProtKB=A0A1U8LJ67	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_026252\|UniProtKB=A0A061F236	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_013G044300v3\|UniProtKB=B9I5L8	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_09G149600\|UniProtKB=A0A2C9VAX2	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0608090\|UniProtKB=B9S7I9	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_10G167200\|UniProtKB=A0A0R4J499	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g079800\|UniProtKB=A0A072VLV5	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr11_10780\|UniProtKB=A0A2I4EXQ4	Juglans regia	O
JUGRE\|EnsemblGenome=Jr11_10770\|UniProtKB=A0A2I4EXP1	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_2G009600\|UniProtKB=A0A0A0LG62	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_6G348100\|UniProtKB=A0A251P3H2	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_110280\|UniProtKB=D8S7F1	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_75970\|UniProtKB=D8QSM4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_235583\|UniProtKB=D8SZ72	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_82799\|UniProtKB=D8R1U6	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c26_7960\|UniProtKB=A0A2K1IC89	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0013s0147\|UniProtKB=A0A2R6XIK8	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_005710020\|UniProtKB=A0A1Y1IG88	Klebsormidium nitens	O
LEIMA\|EnsemblGenome=LMJF_35_3600\|UniProtKB=E9AFI4	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb09.211.2860\|UniProtKB=Q38DL9	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_1248100\|UniProtKB=Q8I4V3	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00004391001\|UniProtKB=A0BCN0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019083001\|UniProtKB=A0DPD4	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_21163\|UniProtKB=B8BTN2	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GY72_PHYRM\|UniProtKB=H3GY72	Phytophthora ramorum	LDO
PHYRM\|Gene=H3G6M3_PHYRM\|UniProtKB=H3G6M3	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_05g239050v5\|UniProtKB=A0A2K3DT13	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00052p00179090\|UniProtKB=U5CT54	Amborella trichopoda	LDO
MUSAM\|EnsemblGenome=Ma08_g05520\|UniProtKB=A0A804K386	Musa acuminata subsp. malaccensis	O
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0351571\|UniProtKB=A0A251U8R7	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C100015660\|UniProtKB=A0A9R1XT09	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a011538mg\|UniProtKB=A0A022Q2G8	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_08198\|UniProtKB=A0A1U8FTP5	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400002574\|UniProtKB=M0ZRQ2	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc03g121870.3\|UniProtKB=A0A3Q7GLL7	Solanum lycopersicum	O
TOBAC\|Gene=LOC107827419\|UniProtKB=A0A1S4D9C7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107772320\|UniProtKB=A0A1S3Y4Y1	Nicotiana tabacum	O
VITVI\|Gene_OrderedLocusName=VIT_09s0002g01820\|UniProtKB=D7TZX1	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_F03163\|UniProtKB=A0A059BV14	Eucalyptus grandis	O
GOSHI\|Gene=LOC107904320\|UniProtKB=A0A1U8JD28	Gossypium hirsutum	O
GOSHI\|Gene=LOC107931611\|UniProtKB=A0A1U8LWT3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_029083\|UniProtKB=A0A061GDH5	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g045799mg\|UniProtKB=A0A067FCS2	Citrus sinensis	O
ZOSMR\|Gene_ORFName=ZOSMA_26G01540\|UniProtKB=A0A0K9PEB1	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma08_g09540\|UniProtKB=A0A804K4Q5	Musa acuminata subsp. malaccensis	LDO
SORBI\|EnsemblGenome=SORBI_3001G507900\|UniProtKB=C5WYU0	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb003510\|UniProtKB=A0A1D6JND9	Zea mays	LDO
BRADI\|EnsemblGenome=BRADI_1g75560v3\|UniProtKB=I1H9V7	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0412180\|UniProtKB=A0A8I6YAV9	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5A02G513400\|UniProtKB=A0A3B6KTP7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G344500\|UniProtKB=A0A3B6IWU6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G339600\|UniProtKB=A0A3B6JR35	Triticum aestivum	LDO
NELNU\|Gene=LOC104600653\|UniProtKB=A0A1U8Q5K6	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110795886\|UniProtKB=A0A9R0IWF1	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr10g0456421\|UniProtKB=A0A9K3I0L5	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400185810\|UniProtKB=A0A9R1VTD3	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a004018mg\|UniProtKB=A0A022S2B5	Erythranthe guttata	LDO
SOLLC\|EnsemblGenome=Solyc08g062770.3\|UniProtKB=A0A3Q7IJ69	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107832162\|UniProtKB=A0A1S4DPV3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107808157\|UniProtKB=A0A1S4BGY8	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_16s0115g00300\|UniProtKB=F6HCN9	Vitis vinifera	LDO
VITVI\|Gene_OrderedLocusName=VIT_16s0115g00070\|UniProtKB=F6HCM6	Vitis vinifera	LDO
BRANA\|Gene_ORFName=GSBRNA2T00058277001\|UniProtKB=A0A078HC17	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra034296\|UniProtKB=M4EZQ3	Brassica campestris	LDO
ARATH\|TAIR=locus=2057756\|UniProtKB=O64850	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107915038\|UniProtKB=A0A1U8KF85	Gossypium hirsutum	O
GOSHI\|Gene=LOC107962831\|UniProtKB=A0A1U8PX58	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_037322\|UniProtKB=A0A061GS31	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g008457mg\|UniProtKB=A0A067G1P1	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_006G225600v3\|UniProtKB=A0A2K2A6G5	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_16G082500\|UniProtKB=A0A2C9U9V9	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0706060\|UniProtKB=B9RQS4	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_17G226800\|UniProtKB=K7MNF0	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_14G097800\|UniProtKB=I1M945	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g015770\|UniProtKB=G7I9V1	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr06_03920\|UniProtKB=A0A2I4DJG7	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G646220\|UniProtKB=A0A0A0L0R5	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G408900\|UniProtKB=M5Y7F0	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_430216\|UniProtKB=D8T8Q4	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_447844\|UniProtKB=D8T2Q8	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c15_20230\|UniProtKB=A0A2K1JDU6	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0046s0004\|UniProtKB=A0A2R6WZC7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000560310\|UniProtKB=A0A1Y1HRV3	Klebsormidium nitens	LDO