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PANTHER™ Pathway Release Calendar

 PANTHER Pathways version 1.3 release in August 2006
  • 23 new pathways, 130 total
  • new pathways include:
    • Adenine and hypoxanthine salvage pathway (P02723)
    • Androgen/estrogene/progesterone biosynthesis (P02727)
    • Biotin biosynthesis (P02731)
    • Cobalamin biosynthesis (P02735)
    • Formyltetrahydroformate biosynthesis (P02743)
    • Histidine biosynthesis (P02747)
    • Lysine biosynthesis (P02751)
    • Methylmalonyl pathway (P02755)
    • Pyridoxal-5-phosphate biosynthesis (P02759)
    • Peptidoglycan biosynthesis (P02763)
    • Phenylpropionate degradation (P02764)
    • Pyrimidine Metabolism (P02771)
    • Salvage pyrimidine ribonucleotides (P02775)
    • Thiamin biosynthesis (P02779)
    • Tryptophan biosynthesis (P02783)
    • Vitamin B6 metabolism (P02787)
    • Beta1 adrenergic receptor signaling pathway (P04377)
    • Beta2 adrenergic receptor signaling pathway (P04378)
    • Beta3 adrenergic receptor signaling pathway (P04379)
    • Gamma-aminobutyric acid synthesis (P04384)
    • Histamine H1 receptor mediated signaling pathway (P04385)
    • Histamine H2 receptor mediated signaling pathway (P04386)
    • Histamine synthesis (P04387)

 PANTHER Pathways version 2.0 release in May 2007
  • Improved Pathway Applet which is compatible with CellDesigner 3.1.
  • 9 new pathways, 139 total
  • new pathways include:
    • 2-arachidonoylglycerol biosynthesis (P05726)
    • Anandamide biosynthesis (P05727)
    • Anandamide degradation (P05728)
    • Bupropion degradation (P05729)
    • Nicotine degradation I (P05732)
    • Nicotine degradation II (P05733)
    • Endogenous cannabinoid signaling (P05730)
    • GABA-B receptor II signaling (P05731)
    • Synaptic vesicle trafficking (P05734)

 PANTHER Pathways version 2.1 release in December 2007
  • 31 new pathways, 165 total
  • new pathways include:
    • Alanine biosynthesis (P02724)
    • Angiotensin II-stimulated signaling through G proteins and beta-arrestin (P05911)
    • Arginine biosynthesis (P02728)
    • Coenzyme A biosynthesis (P02736)
    • Coenzyme A linked carnitine metabolism (P02732)
    • De novo pyrimidine deoxyribonucleotide biosynthesis (P02739)
    • De novo pyrimidine ribonucleotides biosythesis (P02740)
    • Dopamine receptor mediated signaling pathway (P05912)
        -- replace:
            D1/D5 dopamine receptor mediated sigaling pathway (P04381)
            D2/D3/D4 dopamine receptor mediated signaling pathway (P04382)
    • Enkephalin release (P05913)
        -- replace:
            Enkephalin release (P04383)
    • Fructose galactose metabolism (P02744)
    • Isoleucine biosynthesis (P02748)
    • Mannose metabolism (P02752)
    • N-acetylglucosamine metabolism (P02756)
    • Nicotine degradation (P05914)
        -- replace:
            Nicotine degradation I (P05732)
            Nicotine degradation II (P05733)
    • Opioid prodynorphin pathway (P05916)
    • Opioid proenkephalin pathway (P05915)
    • Opioid proopiomelanocortin pathway (P05917)
    • Oxytocin receptor mediated signaling pathway (P04391)
    • PRPP biosynthesis (P02760)
    • Phenylpropionate degradation (P02767)
    • Proline biosynthesis (P02768)
    • Pyruvate metabolism (P02772)
    • Serine glycine biosynthesis (P02776)
    • Thiamin metabolism (P02780)
    • Thyrotropin-releasing hormone receptor signaling pathway (P04394)
    • Tyrosine biosynthesis (P02784)
    • Vasopressin synthesis (P04395)
    • Vitamin D metabolism and pathway (P04396)
    • Xanthine and guanine salvage pathway (P02788)
    • p38 MAPK pathway (P05918)
    • p53 pathway by glucose deprivation (P04397)
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