Pathway Component Details
| Name: | 5HT transporter |
| Definition: | A Na(+)- and Cl(-)-coupled serotonin (5-hydroxytryptamine, 5HT) transporter is expressed on neuronal, platelet, placental, and pulmonary membranes. The brain 5HT transporter appears to be a principal site of action of therapeutic antidepressants and may mediate behavioral and/or toxic effects of cocaine and amphetamines. |
| Category ID: | P04409 |
| Synonyms: | |
| Upstream: | |
| Downstream: | |
| Number Families/Subfamilies: | 1 |
| Number of Associated Sequences: | 7 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: | Medline:7681602 |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR11616:SF40 | P31645 | Sodium-dependent serotonin transporter | IEA | Medline:7681602 |
| F1MLI6 | Transporter | IEA | Medline:7681602 | |
| F1PXA1 | Transporter | ISS | Medline:7681602 | |
| Q60857 | Sodium-dependent serotonin transporter | IEA | Medline:7681602 | |
| P31652 | Sodium-dependent serotonin transporter | IEA | Medline:7681602 | |
| H2QCL1 | Transporter | ISS | Medline:7681602 | |
| F7E2P3 | Transporter | ISS | Medline:7681602 |