| Family: |
ADENOSYLHOMOCYSTEINASE (PTHR23420)
|
| Subfamilies: |
1
|
| PANTHER Links: |
|
| Abstract: |
S-adenosyl-L-homocysteine hydrolase (EC: 3.3.1.1) (AdoHcyase) is an enzyme of
the activated methyl cycle, responsible for the reversible hydration of
S-adenosyl-L-homocysteine into adenosine and homocysteine. AdoHcyase is an
ubiquitous enzyme which binds and requires NAD+ as a cofactor.
AdoHcyase is a highly conserved protein [PMID:1631127] of about 430 to 470 amino acids.
The family contains a glycine-rich region in the central part of AdoHcyase; a region thought to be
involved in NAD-binding.
|
| InterPro Accession: |
IPR000043
|
| PANTHER Molecular Function: |
 Hydrolase
 Other hydrolase
|
| PANTHER Biological Process: |
Nucleoside, nucleotide and nucleic acid metabolism
Purine metabolism
|
| Pathway Categories: |
No pathway information available
|
| Training Sequences: |
58
|
| HMM Length |
431
|
| Downloads: |
HMM (HMMER format) |
