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PANTHER Family Information   
Family: TREHALASE (PTHR23403)
Subfamilies: 2
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract:

O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [PMID:7624375, PMID:8535779, PUB00005672]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site [PUB00007032]. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'.

O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [PMID:1747104, PMID:8352747, PMID:8687420, PMID:1732212, PMID:8535779, PUB00005672]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site [PUB00007032]. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'.

Glycoside hydrolase family 37 CAZY: GH_37 comprises enzymes with only one known activity; trehalase (EC: 3.2.1.28).

Trehalase is the enzyme responsible for the degradation of the disaccharide alpha,alpha-trehalose yielding two glucose subunits [PMID:8444853]. It is an enzyme found in a wide variety of organisms and whose sequence has been highly conserved throughout evolution.


InterPro Accession: IPR001661
PANTHER Molecular Function: Molecular function unclassified

PANTHER Biological Process: Biological process unclassified

Pathway Categories: No pathway information available
Training Sequences: 35
HMM Length 597
Downloads: HMM (HMMER format)

Genes assigned to this Family
  Total Celera FlyBase NCBI
H. sapiens 3 2 0 1
M. musculus 2 1 0 1
R. norvegicus 2 1 0 1
D. melanogaster 2 0 2 0
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