PANTHER Subfamily Information 
| Subfamily: | ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE ALPHA (PTHR22855:SF3) | ||
| Family: | ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED | ||
| PANTHER Links: |
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| Abstract: |
This protein is a subunit of the acetyl coenzyme A carboxylase complex (EC: 6.4.1.2).
It catalyzes the first step in the synthesis of long-chain fatty acids which
involves the carboxylation of acetyl-CoA to malonyl-CoA.
The acetyl-CoA carboxylase complex (EC: 6.4.1.2) is a heterohexamer of biotin carboxyl
carrier protein, biotin carboxylase and two non-identical carboxyl transferase subunits
(alpha and beta) in a 2:2 association [PMID:1355089].
The reaction involves two steps:
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| InterPro Accession: | IPR001095 | ||
| PANTHER Molecular Function: |
 Ligase Other ligase |
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| PANTHER Biological Process: |
Lipid, fatty acid and steroid metabolism Fatty acid metabolism Fatty acid biosynthesis |
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| Pathway Categories: | No pathway information available | ||
| Training Sequences: |
15
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| HMM Length | 547 | ||
| Downloads: | HMM (HMMER format) |
Genes assigned to this Subfamily