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PANTHER Subfamily Information   
Subfamily: MALATE SYNTHASE (PTHR21631:SF1)
Family: ISOCITRATE LYASE/MALATE SYNTHASE
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract:

Malate synthase (EC: 2.3.3.9) catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle in bacteria, fungi and plants. Malate synthase has a TIM beta/alpha-barrel fold [PMID:10715138].


InterPro Accession: IPR001465
PANTHER Molecular Function: Synthase and synthetase
   Synthase
Transferase

PANTHER Biological Process: Carbohydrate metabolism
   Tricarboxylic acid pathway
Nucleoside, nucleotide and nucleic acid metabolism
   Purine metabolism

Pathway Categories: No pathway information available
Training Sequences: 17
HMM Length 471
Downloads: HMM (HMMER format)

Genes assigned to this Subfamily
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