PANTHER Family Information 
| Family: | CHORISMATE SYNTHASE (PTHR21085) | ||
| Subfamilies: | 1 | ||
| PANTHER Links: |
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| Abstract: |
Chorismate synthase (EC: 4.2.3.5) catalyzes the last of the
seven steps in the
shikimate pathway which is used in prokaryotes, fungi and plants for the
biosynthesis of aromatic amino acids. It catalyzes the 1,4-trans elimination
of the phosphate group from 5-enolpyruvylshikimate-3-phosphate (EPSP) to form
chorismate which can then be used in phenylalanine, tyrosine or tryptophan
biosynthesis. Chorismate synthase requires the presence of a reduced flavin
mononucleotide (FMNH2 or FADH2) for its activity.
Chorismate synthase from various sources shows [PMID:1718979,
PMID:1837329] a high degree of sequence
conservation. It is a protein of about 360 to 400 amino-acid residues.
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| InterPro Accession: | IPR000453 | ||
| PANTHER Molecular Function: |
 Synthase and synthetase Other synthase/synthetaseLyase |
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| PANTHER Biological Process: |
Amino acid metabolism Amino acid biosynthesis |
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| Pathway Categories: |
Chorismate biosynthesis Chorismate synthase |
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| Training Sequences: |
21
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| HMM Length | 430 | ||
| Downloads: | HMM (HMMER format) |
Genes assigned to this Family