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PANTHER Subfamily Information   
Subfamily: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE (PTHR21057:SF2)
Family: PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract:

These sequences describe 2-dehydro-3-deoxyphosphooctonate aldolase. Alternate names include 3-deoxy-d-manno-octulosonic acid 8-phosphate and KDO-8 phosphate synthetase. It catalyzes the aldol condensation of phosphoenolpyruvate with D-arabinose 5-phosphate.

phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate

In Gram-negative bacteria, this is the first step in the biosynthesis of 3-deoxy-D-manno-octulosonate, part of the oligosaccharide core of lipopolysaccharide.


InterPro Accession: IPR006269
PANTHER Molecular Function: Transfer/carrier protein
Synthase and synthetase
   Synthase

PANTHER Biological Process: Lipid, fatty acid and steroid metabolism
   Fatty acid metabolism
          Fatty acid biosynthesis

Pathway Categories: No pathway information available
Training Sequences: 9
HMM Length 293
Downloads: HMM (HMMER format)

Genes assigned to this Subfamily
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