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*Now available with Java™ 1.5!*
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| Family: |
RIBOPHORIN I (PTHR21049)
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| Subfamilies: |
1
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| PANTHER Links: |
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| Abstract: |
Ribophorin I is an essential subunit of oligosaccharyltransferase (OST), which is also known as dolichyl-diphosphooligosaccharide--protein glycosyltransferase, (EC: 2.4.1.119). OST catalyses the transfer of an oligosaccharide from dolichol pyrophosphate to selected asparagine residues of nascent polypeptides as they are translocated into the lumen of the rough endoplasmic reticulum. Ribophorin I and OST48 are thought to be responsible for OST catalytic activity [PMID:11443278]. Both yeast and mammalian proteins are glycosylated but the sites are not conserved. Glycosylation may contribute towards general solubility but is unlikely to be involved in a specific biochemical function [PMID:7720878]. Most family members are predicted to have a transmembrane helix at the C terminus of this region.
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| InterPro Accession: |
IPR007676
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| PANTHER Molecular Function: |
Transferase Glycosyltransferase
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| PANTHER Biological Process: |
Protein metabolism and modification Protein biosynthesis Protein modification Protein glycosylation
Other metabolism
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| Pathway Categories: |
No pathway information available
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| Training Sequences: |
21
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| HMM Length |
636
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| Downloads: |
HMM (HMMER format) |
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Total |
Celera |
FlyBase |
NCBI |
| H. sapiens |
2
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1
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0 |
1
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| M. musculus |
2
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1
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0 |
1
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| R. norvegicus |
2
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1
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0 |
1
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| D. melanogaster |
1
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0 |
1
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0 |
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