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PANTHER Family Information   
Family: PEPTIDYL-TRNA HYDROLASE (PTHR17224)
Subfamilies: 1
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract:

Peptidyl-tRNA hydrolase (EC: 3.1.1.29) (PTH) is a bacterial enzyme that cleaves peptidyl-tRNA or N-acyl-aminoacyl-tRNA to yield free peptides or N-acyl-amino acids and tRNA. The natural substrate for this enzyme may be peptidyl-tRNA which drop off the ribosome during protein synthesis [PMID:1833189, PMID:8635758]. Bacterial PTH has been found to be evolutionary related to a yeast protein [PMID:8563640].


InterPro Accession: IPR001328
PANTHER Molecular Function: Hydrolase
   Esterase

PANTHER Biological Process: Protein metabolism and modification
   Protein biosynthesis

Pathway Categories: No pathway information available
Training Sequences: 24
HMM Length 204
Downloads: HMM (HMMER format)

Genes assigned to this Family
  Total Celera NCBI
H. sapiens 2 1 1
M. musculus 2 1 1
R. norvegicus 2 1 1
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