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PANTHER Family Information   
Family: AMELOBLASTIN (PTHR14115)
Subfamilies: 1
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract: This family consists of mammalian Ameloblastin precursor (Amelin) proteins. Matrix proteins of tooth enamel consist mainly of amelogenin but also of non-amelogenin proteins, which, although their volumetric percentage is low, have an important role in enamel mineralization. One of the non-amelogenin proteins is ameloblastin, also known as amelin and sheathlin. Ameloblastin (AMBN) is one of the enamel sheath proteins which is thought to have a role in determining the prismatic structure of growing enamel crystals [PMID:11867231].
InterPro Accession: IPR007798
PANTHER Molecular Function: Extracellular matrix
Miscellaneous function
   Structural protein

PANTHER Biological Process: Developmental processes
   Other developmental process

Pathway Categories: No pathway information available
Training Sequences: 11
HMM Length 425
Downloads: HMM (HMMER format)

Genes assigned to this Family
  Total Celera NCBI
H. sapiens 2 1 1
M. musculus 2 1 1
R. norvegicus 2 1 1
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