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PANTHER Family Information   
Family: PHOSPHATIDYLINOSITOL GLYCAN, CLASS C (PTHR12982)
Subfamilies: 1
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract:

Glycosylphosphatidylinositol (GPI) represents an important anchoring molecule for cell surface proteins. The first step in its synthesis is the transfer of N-acetylglucosamine (GlcNAc) from UDP-N-acetylglucosamine to phosphatidylinositol (PI). This step involves products of three or four genes in both yeast (GPI1, GPI2 and GPI3) and mammals (GPI1, PIG A, PIG H and PIG C), respectively.


InterPro Accession: IPR009450
PANTHER Molecular Function: Transferase
   Glycosyltransferase

PANTHER Biological Process: Lipid, fatty acid and steroid metabolism
   Phospholipid metabolism

Pathway Categories: No pathway information available
Training Sequences: 12
HMM Length 293
Downloads: HMM (HMMER format)

Genes assigned to this Family
  Total Celera FlyBase NCBI
H. sapiens 3 2 0 1
M. musculus 2 1 0 1
R. norvegicus 2 1 0 1
D. melanogaster 1 0 1 0
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