PANTHER Family Information 
| Family: | ALPHA-N-ACETYLGLUCOSAMINIDASE (PTHR12872) | ||
| Subfamilies: | 1 | ||
| PANTHER Links: |
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| Abstract: |
Alpha-N-acetylglucosaminidase is a lysosomal enzyme required for the stepwise degradation of heparan sulphate [PMID:10588735]. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterised by neurological dysfunction but relatively mild somatic manifestations [PMID:12049639].
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| InterPro Accession: | IPR007781 | ||
| PANTHER Molecular Function: |
 OxidoreductaseHydrolase Glycosidase |
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| PANTHER Biological Process: |
Carbohydrate metabolismProtein metabolism and modification Protein modification Protein glycosylation |
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| Pathway Categories: | No pathway information available | ||
| Training Sequences: |
11
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| HMM Length | 776 | ||
| Downloads: | HMM (HMMER format) |
Genes assigned to this Family
| Total | Celera | FlyBase | NCBI | |
| H. sapiens | 2 | 1 | 0 | 1 |
| M. musculus | 2 | 1 | 0 | 1 |
| R. norvegicus | 2 | 1 | 0 | 1 |
| D. melanogaster | 1 | 0 | 1 | 0 |