PANTHER Family Information 
| Family: | TRANSCRIPTION INITIATION FACTOR IA (RRN3) (PTHR12790) | ||
| Subfamilies: | 1 | ||
| PANTHER Links: |
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| Abstract: |
This family consists of several eukaryotic proteins which are homologous to the Saccharomyces cerevisiae RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in the S. cerevisiae [PMID:8670901] RNA polymerase I complex within the nucleolus. In mammalian cells, the phosphorylation state of Rrn3 regulates rDNA transcription by determining the steady-state concentration of the Rrn3 [PMID:12015311]. |
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| InterPro Accession: | IPR007991 | ||
| PANTHER Molecular Function: |
 Transcription factor Basal transcription factor |
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| PANTHER Biological Process: |
Nucleoside, nucleotide and nucleic acid metabolism mRNA transcription mRNA transcription initiation rRNA metabolism |
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| Pathway Categories: |
General transcription by RNA polymerase I RNA Polymerase I Complex |
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| Training Sequences: |
17
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| HMM Length | 693 | ||
| Downloads: | HMM (HMMER format) |
Genes assigned to this Family
| Total | Celera | FlyBase | NCBI | |
| H. sapiens | 5 | 4 | 0 | 1 |
| M. musculus | 2 | 1 | 0 | 1 |
| R. norvegicus | 2 | 1 | 0 | 1 |
| D. melanogaster | 1 | 0 | 1 | 0 |