PANTHER Family Information 
| Family: | NOT56 - RELATED (PTHR12646) | ||
| Subfamilies: | 1 | ||
| PANTHER Links: |
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| Abstract: |
The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl pyrophosphate. Whereas early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9GlcNAc2-PP-Dol on the lumenal side use Dol-P-Man [PMID:11308030]. The ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.
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| InterPro Accession: | IPR007873 | ||
| PANTHER Molecular Function: |
 Transferase Glycosyltransferase |
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| PANTHER Biological Process: |
Carbohydrate metabolism Other polysaccharide metabolismProtein metabolism and modification Protein modification Protein glycosylation |
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| Pathway Categories: | No pathway information available | ||
| Training Sequences: |
13
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| HMM Length | 451 | ||
| Downloads: | HMM (HMMER format) |
Genes assigned to this Family
| Total | Celera | FlyBase | NCBI | |
| H. sapiens | 3 | 2 | 0 | 1 |
| M. musculus | 2 | 1 | 0 | 1 |
| R. norvegicus | 2 | 1 | 0 | 1 |
| D. melanogaster | 1 | 0 | 1 | 0 |