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PANTHER Family Information   
Family: NOT56 - RELATED (PTHR12646)
Subfamilies: 1
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract: The formation of N-glycosidic linkages of glycoproteins involves the ordered assembly of the common Glc3Man9GlcNAc2 core-oligosaccharide on the lipid carrier dolichyl pyrophosphate. Whereas early mannosylation steps occur on the cytoplasmic side of the endoplasmic reticulum with GDP-Man as donor, the final reactions from Man5GlcNAc2-PP-Dol to Man9GlcNAc2-PP-Dol on the lumenal side use Dol-P-Man [PMID:11308030]. The ALG3 gene encodes the Dol-P-Man:Man5GlcNAc2-PP-Dol mannosyltransferase.
InterPro Accession: IPR007873
PANTHER Molecular Function: Transferase
   Glycosyltransferase

PANTHER Biological Process: Carbohydrate metabolism
   Other polysaccharide metabolism
Protein metabolism and modification
   Protein modification
          Protein glycosylation

Pathway Categories: No pathway information available
Training Sequences: 13
HMM Length 451
Downloads: HMM (HMMER format)

Genes assigned to this Family
  Total Celera FlyBase NCBI
H. sapiens 3 2 0 1
M. musculus 2 1 0 1
R. norvegicus 2 1 0 1
D. melanogaster 1 0 1 0
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