| Family: |
RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED (PTHR12122)
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| Subfamilies: |
2
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| PANTHER Links: |
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| Abstract: |
Retinal rod and cone cGMP phosphodiesterases function as the effector enzymes in the vertebrate visual transduction cascade. This family represents the inhibitory gamma subunit [PMID:11900530], which is also expressed outside retinal tissues and has been shown to interact with the G-protein-coupled receptor kinase 2 signalling system to regulate the epidermal growth factor- and thrombin-dependent stimulation of p42/p44 mitogen-activated protein kinase in human embryonic kidney 293 cells [PMID:11502744].
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| InterPro Accession: |
IPR006952
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| PANTHER Molecular Function: |
Hydrolase Esterase Phosphodiesterase
Miscellaneous function Other miscellaneous function protein
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| PANTHER Biological Process: |
Biological process unclassified
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| Pathway Categories: |
No pathway information available
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| Training Sequences: |
18
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| HMM Length |
87
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| Downloads: |
HMM (HMMER format) |