| Family: |
RETINAL CONE RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE GAMMA-SUBUNIT-RELATED (PTHR12122)
|
| Subfamilies: |
2
|
| PANTHER Links: |
|
| Abstract: |
Retinal rod and cone cGMP phosphodiesterases function as the effector enzymes in the vertebrate visual transduction cascade. This family represents the inhibitory gamma subunit [PMID:11900530], which is also expressed outside retinal tissues and has been shown to interact with the G-protein-coupled receptor kinase 2 signalling system to regulate the epidermal growth factor- and thrombin-dependent stimulation of p42/p44 mitogen-activated protein kinase in human embryonic kidney 293 cells [PMID:11502744].
|
| InterPro Accession: |
IPR006952
|
| PANTHER Molecular Function: |
 Hydrolase
 Esterase
Phosphodiesterase
Miscellaneous function
Other miscellaneous function protein
|
| PANTHER Biological Process: |
Biological process unclassified
|
| Pathway Categories: |
No pathway information available
|
| Training Sequences: |
18
|
| HMM Length |
87
|
| Downloads: |
HMM (HMMER format) |
