|
|
|
|
|
|
|
|
*Now available with Java™ 1.5!*
|
|
|
|
| Family: |
GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE (PTHR11999)
|
| Subfamilies: |
14
|
| PANTHER Links: |
|
| Abstract: |
A number of pyridoxal-dependent decarboxylases share regions of sequence similarity, particularly in the vicinity of a conserved lysine residue, which provides the attachment site for the pyridoxal-phosphate (PLP) group [PMID:8181483, PMID:2124279]. Among these enzymes are aromatic-L-amino-acid decarboxylase (L-dopa decarboxylase or tryptophan decarboxylase), which catalyses the decarboxylation of tryptophan to tryptamine [PMID:8889823]; tyrosine decarboxylase, which converts tyrosine into tyramine; and histidine decarboxylase, which catalyses the decarboxylation of histidine to histamine [PMID:2300558]. These enzymes belong to the group II decarboxylases [PMID:8181483, PMID:8889823].
|
| InterPro Accession: |
IPR002129
|
| PANTHER Molecular Function: |
Lyase Decarboxylase
|
| PANTHER Biological Process: |
Amino acid metabolism Other amino acid metabolism
|
| Pathway Categories: |
No pathway information available
|
| Training Sequences: |
151
|
| HMM Length |
564
|
| Downloads: |
HMM (HMMER format) |
| |
Total |
Celera |
FlyBase |
NCBI |
| H. sapiens |
20
|
10
|
0 |
10
|
| M. musculus |
18
|
9
|
0 |
9
|
| R. norvegicus |
16
|
8
|
0 |
8
|
| D. melanogaster |
10
|
0 |
10
|
0 |
|