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*Now available with Java™ 1.5!*
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| Family: |
UDP- GLUCOSE PYROPHOSPHORYLASE (PTHR11952)
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| Subfamilies: |
2
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| PANTHER Links: |
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| Abstract: |
This family consists of UTP--glucose-1-phosphate uridylyltransferases, EC: 2.7.7.9. Also known as UDP-glucose pyrophosphorylase (UDPGP) and Glucose-1-phosphate uridylyltransferase. UTP--glucose-1-phosphate uridylyltransferase catalyses the interconversion of MgUTP + glucose-1-phosphate and UDP-glucose + MgPPi [PMID:8631325]. UDP-glucose is an important intermediate in mammalian carbohydrate interconversion involved in various metabolic roles depending on tissue type [PMID:8631325]. In Dictyostelium discoideum (slime mold), mutants in this enzyme abort the development cycle [PMID:3035502]. Also within this family is UDP-N-acetylglucosamine pyrophosphorylase (SWISSPROT: Q16222) [PMID:9603950] and two hypothetical proteins from Borrelia burgdorferi, the lyme disease spirochaete (SWISSPROT: O51893 and SWISSPROT: O51036).
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| InterPro Accession: |
IPR002618
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| PANTHER Molecular Function: |
Transferase
 Nucleotidyltransferase
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| PANTHER Biological Process: |
Biological process unclassified
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| Pathway Categories: |
No pathway information available
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| Training Sequences: |
81
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| HMM Length |
593
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| Downloads: |
HMM (HMMER format) |
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Total |
Celera |
FlyBase |
NCBI |
| H. sapiens |
7
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4
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0 |
3
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| M. musculus |
6
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2
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0 |
4
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| R. norvegicus |
8
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4
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0 |
4
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| D. melanogaster |
2
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0 |
2
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0 |
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