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PANTHER Family Information   
Family: PHOSPHOGLYCERATE MUTASE (PTHR11931)
Subfamilies: 1
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract:

Most members of this family are phosphoglycerate mutase (EC: 5.4.2.1). This enzyme interconverts 2-phosphoglycerate and 3-phosphoglycerate. 2-phospho-D-glycerate + 2,3-diphosphoglycerate = 3-phospho-D-glycerate + 2,3-diphosphoglycerate. The enzyme is transiently phosphorylated on an active site histidine by 2,3-diphosphoglyerate, which is both substrate and product. Some members of this family have are phosphoglycerate mutase as a minor activity and act primarily as a bisphoglycerate mutase, interconverting 2,3-diphosphoglycerate and 1,3-diphosphoglycerate (EC: 5.4.2.4).


InterPro Accession: IPR005952
PANTHER Molecular Function: Isomerase
   Mutase

PANTHER Biological Process: Carbohydrate metabolism
   Glycolysis

Pathway Categories: Glycolysis
   Phosphoglyceromutase
Training Sequences: 55
HMM Length 254
Downloads: HMM (HMMER format)

Genes assigned to this Family
  Total Celera FlyBase NCBI
H. sapiens 22 14 0 8
M. musculus 17 9 0 8
R. norvegicus 7 4 0 3
D. melanogaster 3 0 3 0
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