PANTHER Family Information 
| Family: | METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE (PTHR11904) | ||
| Subfamilies: | 2 | ||
| PANTHER Links: |
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| Abstract: |
Phosphorylases that belong to the same family include, purine nucleoside phosphorylase (EC: 2.4.2.1) (PNP) from mammals as well as from some bacteria (gene deoD) ( catalyzes the cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules) [PMID:2104852], 5'-methylthioadenosine phosphorylase (EC: 2.4.2.28) (MTA phosphorylase) from eukaryotes [PMID:8687427] and xanthosine phosphorylase (EC: 2.4.2.-) from Escherichia coli (gene xapA) (degrades all purine nucleosides except adenosine and deoxyadenosine) [PMID:7559336]. Most bacterial PNP and archaebacterial MTA phosphorylases belong to a different group of phosphorylases INTERPRO: IPR000845. A number of uncharacterized proteins also belong to this group. |
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| InterPro Accession: | IPR001369 | ||
| PANTHER Molecular Function: |
 Transferase Phosphorylase |
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| PANTHER Biological Process: |
Nucleoside, nucleotide and nucleic acid metabolism Purine metabolism |
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| Pathway Categories: | No pathway information available | ||
| Training Sequences: |
62
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| HMM Length | 381 | ||
| Downloads: | HMM (HMMER format) |
Genes assigned to this Family
| Total | Celera | FlyBase | NCBI | |
| H. sapiens | 7 | 4 | 0 | 3 |
| M. musculus | 6 | 2 | 0 | 4 |
| R. norvegicus | 5 | 3 | 0 | 2 |
| D. melanogaster | 4 | 0 | 4 | 0 |