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Phosphorylases that belong to the same family include, purine nucleoside phosphorylase
(EC: 2.4.2.1) (PNP) from mammals as well as from some bacteria (gene deoD) (
catalyzes the cleavage of guanosine or inosine to respective bases and sugar-1-phosphate
molecules) [PMID:2104852], 5'-methylthioadenosine
phosphorylase (EC: 2.4.2.28) (MTA phosphorylase) from eukaryotes [PMID:8687427] and xanthosine phosphorylase
(EC: 2.4.2.-) from Escherichia coli (gene xapA) (degrades all purine nucleosides
except adenosine and deoxyadenosine) [PMID:7559336].
Most bacterial PNP and archaebacterial MTA phosphorylases belong to a different group of
phosphorylases INTERPRO: IPR000845. A number of uncharacterized proteins also belong to this
group.
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