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*Now available with Java™ 1.5!*
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| Family: |
GLYCEROL-3-PHOSPHATE DEHYDROGENASE (PTHR11728)
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| Subfamilies: |
1
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| PANTHER Links: |
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| Abstract: |
NAD-dependent glycerol-3-phosphate dehydrogenase (EC: 1.1.1.8) (GPD) catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate. It is a cytoplasmic protein, active as a homodimer [PMID:2500660], each monomer containing an N-terminal NAD binding site [PMID:6773774]. In insects, it acts in conjunction with a mitochondrial alpha-glycerophosphate oxidase in the alpha-glycerophosphate cycle, which is essential for the production of energy used in insect flight [PMID:2500660].
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| InterPro Accession: |
IPR006168
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| PANTHER Molecular Function: |
Oxidoreductase
 Dehydrogenase
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| PANTHER Biological Process: |
Lipid, fatty acid and steroid metabolism
Phospholipid metabolism
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| Pathway Categories: |
No pathway information available
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| Training Sequences: |
58
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| HMM Length |
357
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| Downloads: |
HMM (HMMER format) |
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Total |
Celera |
FlyBase |
NCBI |
| H. sapiens |
4
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2
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0 |
2
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| M. musculus |
8
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4
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0 |
4
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| R. norvegicus |
7
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3
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0 |
4
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| D. melanogaster |
3
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0 |
3
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0 |
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