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*Now available with Java™ 1.5!*
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| Family: |
LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (PTHR11717)
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| Subfamilies: |
4
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| PANTHER Links: |
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| Abstract: |
Low molecular weight (LMW) phosphotyrosine protein phosphatase (or acid
phosphatase) acts on tyrosine phosphorylated proteins, low-MW aryl
phosphates and natural and synthetic acyl phosphates [PMID:1587862, PMID:1304913]. It is a
cytoplasmic enzyme that catalyses the reaction:
protein tyrosine phosphate + H2O = protein tyrosine + Pi
The structure of the protein has been solved by X-ray crystallography [PMID:8052313]
and is found to form a single structural domain. It belongs to the
alpha/beta class, with 6 alpha-helices and 4 beta-strands forming a 3-layer
alpha-beta-alpha sandwich architecture.
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| InterPro Accession: |
IPR000106
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| PANTHER Molecular Function: |
Molecular function unclassified
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| PANTHER Biological Process: |
Biological process unclassified
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| Pathway Categories: |
No pathway information available
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| Training Sequences: |
50
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| HMM Length |
149
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| Downloads: |
HMM (HMMER format) |
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Total |
Celera |
FlyBase |
NCBI |
| H. sapiens |
4
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2
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0 |
2
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| M. musculus |
13
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7
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0 |
6
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| R. norvegicus |
7
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2
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0 |
5
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| D. melanogaster |
4
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0 |
4
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0 |
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