PANTHER Family Information 
| Family: | PYRROLINE-5-CARBOXYLATE REDUCTASE (PTHR11645) | ||
| Subfamilies: | 1 | ||
| PANTHER Links: |
|
||
| Abstract: |
Delta 1-pyrroline-5-carboxylate reductase (P5CR) (EC: 1.5.1.2) [PMID:2199815, PMID:2107123] is the enzyme that catalyzes the terminal step in the biosynthesis of proline from glutamate, the NAD(P) dependent oxidation of 1-pyrroline-5-carboxylate into proline.
|
||
| InterPro Accession: | IPR000304 | ||
| PANTHER Molecular Function: |
 Oxidoreductase Reductase |
||
| PANTHER Biological Process: |
Amino acid metabolism Amino acid biosynthesis |
||
| Pathway Categories: |
Proline biosynthesis Pyrroline-5-carboxylate reductase |
||
| Training Sequences: |
53
|
||
| HMM Length | 313 | ||
| Downloads: | HMM (HMMER format) |
Genes assigned to this Family
| Total | Celera | FlyBase | NCBI | |
| H. sapiens | 8 | 4 | 0 | 4 |
| M. musculus | 6 | 3 | 0 | 3 |
| R. norvegicus | 8 | 4 | 0 | 4 |
| D. melanogaster | 2 | 0 | 2 | 0 |