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PANTHER Family Information   
Family: PYRROLINE-5-CARBOXYLATE REDUCTASE (PTHR11645)
Subfamilies: 1
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract: Delta 1-pyrroline-5-carboxylate reductase (P5CR) (EC: 1.5.1.2) [PMID:2199815, PMID:2107123] is the enzyme that catalyzes the terminal step in the biosynthesis of proline from glutamate, the NAD(P) dependent oxidation of 1-pyrroline-5-carboxylate into proline.
InterPro Accession: IPR000304
PANTHER Molecular Function: Oxidoreductase
   Reductase

PANTHER Biological Process: Amino acid metabolism
   Amino acid biosynthesis

Pathway Categories: Proline biosynthesis
   Pyrroline-5-carboxylate reductase
Training Sequences: 53
HMM Length 313
Downloads: HMM (HMMER format)

Genes assigned to this Family
  Total Celera FlyBase NCBI
H. sapiens 8 4 0 4
M. musculus 6 3 0 3
R. norvegicus 8 4 0 4
D. melanogaster 2 0 2 0
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