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PANTHER Family Information   
Family: PSEUDOURIDYLATE SYNTHASE (PTHR11142)
Subfamilies: 1
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract: Transfer RNA-pseudouridine synthetase contains one atom of zinc essential for its native conformation and tRNA recognition [PMID:9585540] and has a strictly conserved aspartic acid that is likely to be involved in catalysis. It is involved in the formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer-RNAs. Pseudouridine is the most abundant modified nucleoside found in all cellular RNAs.
InterPro Accession: IPR001406
PANTHER Molecular Function: Synthase and synthetase
   Synthase
Lyase
   Other lyase

PANTHER Biological Process: Nucleoside, nucleotide and nucleic acid metabolism
   tRNA metabolism

Pathway Categories: No pathway information available
Training Sequences: 55
HMM Length 412
Downloads: HMM (HMMER format)

Genes assigned to this Family
  Total Celera FlyBase NCBI
H. sapiens 6 3 0 3
M. musculus 6 3 0 3
R. norvegicus 6 3 0 3
D. melanogaster 2 0 2 0
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