PANTHER Family Information 
| Family: | INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN (PTHR11067) | ||
| Subfamilies: | 2 | ||
| PANTHER Links: |
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| Abstract: |
This family contains the Saccharomyces cerevisiae HAM1 protein SWISSPROT: P47119 and other hypothetical archaeal, bacterial and Caenorhabditis elegans proteins. Saccharomyces cerevisiae HAM1 protects against the mutagenic effects of the base analog 6-N-hydroxylaminopurine (HAP) which can be a natural product of monooxygenase activity on adenine. HAM1 protein protects the cell from HAP, either on the level of deoxynucleoside triphosphate or the DNA level by a yet unidentified set of reactions [PMID:8789257]. |
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| InterPro Accession: | IPR002637 | ||
| PANTHER Molecular Function: |
 Phosphatase Nucleotide phosphatase |
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| PANTHER Biological Process: |
Nucleoside, nucleotide and nucleic acid metabolism Regulation of nucleoside, nucleotide metabolism |
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| Pathway Categories: | No pathway information available | ||
| Training Sequences: |
25
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| HMM Length | 213 | ||
| Downloads: | HMM (HMMER format) |
Genes assigned to this Family
| Total | Celera | FlyBase | NCBI | |
| H. sapiens | 2 | 1 | 0 | 1 |
| M. musculus | 2 | 1 | 0 | 1 |
| R. norvegicus | 2 | 1 | 0 | 1 |
| D. melanogaster | 1 | 0 | 1 | 0 |