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PANTHER Family Information   
Family: COPROPORPHYRINOGEN III OXIDASE (PTHR10755)
Subfamilies: 1
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract: Coprogen oxidase (i.e. coproporphyrin III oxidase or coproporphyrinogenase) catalyses the oxidative decarboxylation of coproporphyrinogen III to proto-porhyrinogen IX in the haem and chlorophyll biosynthetic pathways [PMID:8407975, PMID:8219054]. The protein is a homodimer containing two internally bound iron atoms per molecule of native protein [PMID:3516695]. The enzyme is active in the presence of molecular oxygen that acts as an electron acceptor). The enzyme is widely distributed having been found in a variety of eukaryotic and prokaryotic sources.
InterPro Accession: IPR001260
PANTHER Molecular Function: Oxidoreductase
   Oxidase

PANTHER Biological Process: Coenzyme and prosthetic group metabolism
   Coenzyme metabolism
   Porphyrin metabolism

Pathway Categories: Heme biosynthesis
   Coproporphyrinogen Oxidase (oxygen dependent)
Training Sequences: 19
HMM Length 220
Downloads: HMM (HMMER format)

Genes assigned to this Family
  Total Celera FlyBase NCBI
H. sapiens 2 1 0 1
M. musculus 2 1 0 1
R. norvegicus 2 1 0 1
D. melanogaster 1 0 1 0
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