PANTHER Family Information 
| Family: | COPROPORPHYRINOGEN III OXIDASE (PTHR10755) | ||
| Subfamilies: | 1 | ||
| PANTHER Links: |
|
||
| Abstract: |
Coprogen oxidase (i.e. coproporphyrin III oxidase or coproporphyrinogenase) catalyses
the oxidative decarboxylation of coproporphyrinogen III to proto-porhyrinogen IX in the
haem and chlorophyll biosynthetic pathways [PMID:8407975, PMID:8219054]. The protein is a
homodimer containing two internally bound iron atoms per molecule of native protein
[PMID:3516695]. The enzyme is active in the presence of molecular oxygen that acts
as an electron acceptor). The enzyme is widely distributed having been found in a variety of eukaryotic and
prokaryotic sources.
|
||
| InterPro Accession: | IPR001260 | ||
| PANTHER Molecular Function: |
 Oxidoreductase Oxidase |
||
| PANTHER Biological Process: |
Coenzyme and prosthetic group metabolism Coenzyme metabolism Porphyrin metabolism |
||
| Pathway Categories: |
Heme biosynthesis Coproporphyrinogen Oxidase (oxygen dependent) |
||
| Training Sequences: |
19
|
||
| HMM Length | 220 | ||
| Downloads: | HMM (HMMER format) |
Genes assigned to this Family
| Total | Celera | FlyBase | NCBI | |
| H. sapiens | 2 | 1 | 0 | 1 |
| M. musculus | 2 | 1 | 0 | 1 |
| R. norvegicus | 2 | 1 | 0 | 1 |
| D. melanogaster | 1 | 0 | 1 | 0 |