PANTHER Family Information 
| Family: | DEFENDER AGAINST CELL DEATH (PTHR10705) | ||
| Subfamilies: | 1 | ||
| PANTHER Links: |
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| Abstract: |
Members of this family are thought to be integral membrane
proteins. Some members of this family have been shown to
cause apoptosis if mutated [PMID:8413235], these proteins are known as
DAD for defender against death. The family also includes
the epsilon subunit of the oligosaccharyltransferase that
is involved in N-linked glycosylation [PMID:7593165].
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| InterPro Accession: | IPR003038 | ||
| PANTHER Molecular Function: |
 Transferase Glycosyltransferase |
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| PANTHER Biological Process: |
Protein metabolism and modification Protein modification Protein glycosylationApoptosis Inhibition of apoptosis |
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| Pathway Categories: | No pathway information available | ||
| Training Sequences: |
14
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| HMM Length | 128 | ||
| Downloads: | HMM (HMMER format) |
Genes assigned to this Family
| Total | Celera | FlyBase | NCBI | |
| H. sapiens | 2 | 1 | 0 | 1 |
| M. musculus | 2 | 1 | 0 | 1 |
| R. norvegicus | 2 | 1 | 0 | 1 |
| D. melanogaster | 1 | 0 | 1 | 0 |