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PANTHER Subfamily Information   
Subfamily: EPSILON-TRIMETHYLLYSINE 2-OXOGLUTARATE DIOXYGENASE (PTHR10696:SF2)
Family: GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED
PANTHER Links:
Tree  Multiple Sequence Alignment
Tree  MSA
Abstract:

Members of this family with known function act as trimethyllysine dioxygenase, an enzyme in the pathway for carnitine biosynthesis from lysine. This enzyme is homologous to gamma-butyrobetaine,2-oxoglutarate dioxygenase, which catalyzes the last step in carnitine biosynthesis. Members of this family appear to be eukaryotic only.


InterPro Accession: IPR012776
PANTHER Molecular Function: Oxidoreductase
   Oxygenase
   Hydroxylase

PANTHER Biological Process: Coenzyme and prosthetic group metabolism

Pathway Categories: No pathway information available
Training Sequences: 14
HMM Length 437
Downloads: HMM (HMMER format)

Genes assigned to this Subfamily
  Total Celera FlyBase NCBI
H. sapiens 4 2 0 2
M. musculus 2 1 0 1
R. norvegicus 2 1 0 1
D. melanogaster 1 0 1 0
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