PANTHER Family Information 
| Family: | GLYCOGEN SYNTHASE (PTHR10176) | ||
| Subfamilies: | 1 | ||
| PANTHER Links: |
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| Abstract: |
This family consists of the eukaryotic glycogen synthase proteins GYS1, GYS2 and GYS3. Glycogen synthase (GS) is the enzyme responsible for the synthesis of -1,4-linked glucose chains in glycogen. It is the rate limiting enzyme in the synthesis of the polysaccharide, and its activity is highly regulated through phosphorylation at multiple sites and also by allosteric effectors, mainly glucose 6-phosphate (G6P) [PMID:11415431].
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| InterPro Accession: | IPR008631 | ||
| PANTHER Molecular Function: |
 Synthase and synthetase SynthaseTransferase Glycosyltransferase |
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| PANTHER Biological Process: |
Carbohydrate metabolism Glycogen metabolism |
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| Pathway Categories: |
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway Glycogen synthase D |
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| Training Sequences: |
24
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| HMM Length | 738 | ||
| Downloads: | HMM (HMMER format) |
Genes assigned to this Family
| Total | Celera | FlyBase | NCBI | |
| H. sapiens | 4 | 2 | 0 | 2 |
| M. musculus | 5 | 2 | 0 | 3 |
| R. norvegicus | 6 | 2 | 0 | 4 |
| D. melanogaster | 1 | 0 | 1 | 0 |